Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia.

Autor: Alanazi AD; Department of Biological Sciences, Faculty of Science and Humanities, Shaqra University, P.O. Box 1040, Ad-Dawadimi, 11911, Saudi Arabia., Alouffi AS; King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia., Alyousif MS; Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia., Rahi AA; Department of Biology, College of Science, University of Wasit, Kut, Wasit, 00964, Iraq., Ali MA; Department of Biology, College of Science, University of Wasit, Kut, Wasit, 00964, Iraq., Abdullah HHAM; Department of Parasitology and Animal Diseases, Veterinary Research Division, National Research Centre, 33 Bohouth St., Dokki, Giza, 12622, Egypt., Brayner FA; Laboratório de Imunopatologia Keizo Asami, Universidade Federal de Pernambuco, CEP, Recife, 50670-901, Brazil., Mendoza-Roldan JA; Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Bari, Italy., Bezerra-Santos MA; Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Bari, Italy., Otranto D; Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Bari, Italy. domenico.otranto@uniba.it.; Faculty of Veterinary Sciences, Bu-Ali Sina University, Hamadan, Iran. domenico.otranto@uniba.it.
Jazyk: angličtina
Zdroj: Parasitology research [Parasitol Res] 2021 Dec; Vol. 120 (12), pp. 4241-4246. Date of Electronic Publication: 2021 May 04.
DOI: 10.1007/s00436-021-07166-z
Abstrakt: Leishmania major and Leishmania tropica cause cutaneous leishmaniasis in humans and dogs in several parts of the world, with a large number of cases recorded in the Middle East. However, when they occur in sympatry, the role of each species of Leishmania in the epidemiology of cutaneous leishmaniasis (CL) is not clear. To assess the frequency and to identify the species of Leishmania that infect humans and stray dogs in Riyadh and Al-Qaseem (Saudi Arabia), 311 stray dogs and 27 human patients who were suspected for Leishmania infection were examined for CL by a nested polymerase chain reaction (nPCR). Seven (25.9%) out of 27 human patients scored positive for Leishmania spp. (i.e., L. major in five patients from Riyadh and L. tropica in two patients from Al-Qaseem). Out of 311 dogs, five (1.6%) were infected by L. tropica. Data herein presented demonstrate the occurrence of L. tropica in dogs and humans in Saudi Arabia, as well as the occurrence of L. major in humans.
(© 2021. The Author(s).)
Databáze: MEDLINE
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