Cytologic, histopathologic, and clinical features of granulomatous colitis in a French Bulldog.

Autor: Conrado FO; Department of Comparative, Diagnostic, & Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA., Jones EA; Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA., Graham EA; Department of Comparative, Diagnostic, & Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA., Simpson KW; Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA., Craft WF; Department of Comparative, Diagnostic, & Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA., Beatty SSK; Department of Comparative, Diagnostic, & Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
Jazyk: angličtina
Zdroj: Veterinary clinical pathology [Vet Clin Pathol] 2022 Feb; Vol. 50 Suppl 1, pp. 76-82. Date of Electronic Publication: 2021 May 03.
DOI: 10.1111/vcp.12944
Abstrakt: A young French Bulldog was presented with clinical signs of chronic gastrointestinal disease, unresponsive to medical therapies. Parasite screenings and abdominal ultrasound failed to identify the etiology of the clinical signs. Cytologic evaluation of a rectal scraping sample diagnosed presumptive granulomatous colitis (GC) based on the presence of numerous macrophages with characteristic abundant, pink, granular cytoplasm, which showed an intense pink color when stained with periodic acid-Schiff. Tissue biopsy samples and Escherichia coli fluorescence in situ hybridization analysis confirmed the cytologic diagnosis. The cytologic, histopathologic, and clinical features and staining properties of GC in a French Bulldog are reported. Rectal scraping should be considered a part of the diagnostic evaluation in patients with suspected GC.
(© 2021 American Society for Veterinary Clinical Pathology.)
Databáze: MEDLINE
Externí odkaz: