Prospective analysis of SARS-CoV-2 dissemination to environmental surfaces during endoscopic procedures.

Autor: Somerville CC; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States., Shoaib M; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, United States.; Department of Emergency Medicine, The Feinstein Institutes for Medical Research, Manhasset, New York, United States., Kuschner CE; Department of Emergency Medicine, Northwell Health, New York, United States., Brune Z; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States.; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, United States., Trindade AJ; Division of Gastroenterology, Long Island Jewish Medical Center, Zucker School of Medicine at Hofstra/Northwell, Northwell Health, New Hyde Park, New York, United States., Benias PC; Division of Gastroenterology, Long Island Jewish Medical Center, Zucker School of Medicine at Hofstra/Northwell, Northwell Health, New Hyde Park, New York, United States., Becker LB; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, United States.; Department of Emergency Medicine, The Feinstein Institutes for Medical Research, Manhasset, New York, United States.; Department of Emergency Medicine, Northwell Health, New York, United States.
Jazyk: angličtina
Zdroj: Endoscopy international open [Endosc Int Open] 2021 May; Vol. 9 (5), pp. E701-E705. Date of Electronic Publication: 2021 Apr 22.
DOI: 10.1055/a-1395-6946
Abstrakt: Background and study aims  The COVID-19 pandemic has disrupted routine medical care due to uncertainty regarding the risk of viral spread. One major concern for viral transmission to both patients and providers is performing aerosol-generating procedures such as endoscopy. As such, we performed a prospective study to examine the extent of viral contamination present in the local environment before and after endoscopic procedures on COVID-19 positive patients. Materials and methods  A total of 82 samples were collected from 23 surfaces in the procedure area of four COVID-positive patients undergoing upper endoscopic procedures. Samples were collected both before and after the procedure. severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was extracted and quantified using reverse transcription quantitative polymerase chain reaction with primers to detect nucleocapsid RNA, and results reported as the number of viral copies per square centimeter of contaminated surface. Results  A total of six positive samples were detected from three of the four patients. The floor beneath the patient bed was the most common site of viral RNA, but RNA was also detected on the ventilator monitor prior to the procedure and the endoscope after the procedure. Conclusions  The risk of SARS-CoV-2 transmission associated with upper endoscopy procedures is low based on the low rate of surface contamination. Some surfaces in close proximity to the patient and endoscopist may pose a higher risk for contamination. Patient positioning and oxygen delivery methods may influence the directionality and extent of viral spread. Our results support the use of appropriate personal protection to minimize risk of viral transmission.
Competing Interests: Competing interests Drs. Kuschner and Brune are scientific consultants for RXR Realty. Dr. Trindade is a consultant for Olympus America and Pentax America with research support received from Ninepoint Medical. Dr. Benias is a consultant for Medtronic, Olympus, and Fujinon.
(The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
Databáze: MEDLINE
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