Epidemiological and Clinical Characteristics of COVID-19: A Retrospective Multi-Center Study in Pakistan.

Autor:	Ahmad M; Department of Pharmacology, Riphah International University, Lahore, Pakistan., Beg BM; Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Majeed A; Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Areej S; Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Riffat S; Department of Pharmacology, Riphah International University, Lahore, Pakistan., Rasheed MA; Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Mahmood S; Department of Botany, Division of Science and Technology, University of Education, Lahore, Pakistan., Mushtaq RMZ; Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Hafeez MA; Department of Parasitology, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Jazyk:	angličtina
Zdroj:	Frontiers in public health [Front Public Health] 2021 Apr 14; Vol. 9, pp. 644199. Date of Electronic Publication: 2021 Apr 14 (Print Publication: 2021).
DOI:	10.3389/fpubh.2021.644199
Abstrakt:	The emergence of a pathogen responsible for a mysterious respiratory disease was identified in China and later called a novel coronavirus. This disease was named COVID-19. The present study seeks to determine the epidemiological and clinical characteristics of COVID-19 in Pakistan. This report will exhibit a linkage between epidemiology and clinical aspects which in turn can be helpful to prevent the transmission of the virus in Pakistan. A retrospective, multiple center study was performed by collecting the data from patients' with their demographics, epidemiological status, history of co-morbid conditions, and clinical manifestations of the disease. The data was collected from 31 public-sector and 2 private hospitals across Pakistan by on-field healthcare workers. A Chi-square test was applied to assess the relationship between categorical data entries. A total of 194 medical records were examined. The median age of these patients was found to be 34 years. A total of 53.6% active cases were present including 41.2% males and 12.4% females till the end of the study. Adults accounted for most of the cases (94.3%) of COVID-19. Fever (86.60%), cough (85.05%), fatigue (36.60%), dyspnea (24.74%), and gastrointestinal discomfort (10.31%) were among the most frequently reported signs and symptoms by the patients. However, 4.12% of the total patient population remained asymptomatic. The median duration of hospital stay was found to be 14 (0-19) days. The earliest source of the spread of the virus may be linked to the foreigners traveling to Pakistan. Spread among men was more as compared to women. A few cases were found to be positive, due to the direct contact with pets or livestock. Hypertension (7.73%), diabetes (4.64%), cardiovascular conditions (2.58%) were the most common co-morbidities. The percentage mortality was 2.50% with the highest mortality among elders. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2021 Ahmad, Beg, Majeed, Areej, Riffat, Rasheed, Mahmood, Mushtaq and Hafeez.)
Databáze:	MEDLINE
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