Patient Preferences and Treatment Decisions for Prostate Cancer: Results From A Statewide Urological Quality Improvement Collaborative.

Autor: Paudel R; Department of Learning Health Sciences, University of Michigan, Ann Arbor, MI. Electronic address: rpaudel@med.umich.edu., Ferrante S; Michigan Urological Surgery Improvement Collaborative, Ann Arbor, MI., Qi J; Michigan Urological Surgery Improvement Collaborative, Ann Arbor, MI., Dunn RL; Michigan Urological Surgery Improvement Collaborative, Ann Arbor, MI., Berry DL; Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA., Semerjian A; Michigan Urological Surgery Improvement Collaborative, Ann Arbor, MI; IHA Urology, St. Joseph Mercy Health System, Ypsilanti, MI., Brede CM; Spectrum Health, Grand Rapids, MI., George AK; Michigan Urological Surgery Improvement Collaborative, Ann Arbor, MI; Department of Urology, University of Michigan, Ann Arbor, MI., Lane BR; Spectrum Health, Grand Rapids, MI., Ginsburg KB; Department of Urology, Wayne State University School of Medicine, Detroit, MI; Department of Surgical Oncology, Division of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, PA., Montie JE; Michigan Urological Surgery Improvement Collaborative, Ann Arbor, MI; Department of Urology, University of Michigan, Ann Arbor, MI., Lane GI; Department of Urology, University of Michigan, Ann Arbor, MI.
Jazyk: angličtina
Zdroj: Urology [Urology] 2021 Sep; Vol. 155, pp. 55-61. Date of Electronic Publication: 2021 Apr 29.
DOI: 10.1016/j.urology.2021.04.020
Abstrakt: Objectives: To examine the relationship between influential factors and treatment decisions among men with newly diagnosed prostate cancer (PCa).
Methods: We identified men in the Michigan Urological Surgery Improvement Collaborative registry diagnosed with localized PCa between 2018-2020 who completed Personal Patient Profile-Prostate. We analyzed the proportion of active surveillance (AS) between men who stated future bladder, bowel, and sexual problems (termed influential factors) had "a lot of influence" on their treatment decisions versus other responses. We also assessed the relationship between influential factors, confirmatory testing results and choice of AS.
Results: A total of 509 men completed Personal Patient Profile-Prostate. Treatment decisions aligned with influential factors for 88% of men with favorable risk and 49% with unfavorable risk PCa. A higher proportion of men who identified bladder, bowel and sexual concerns as having "a lot of influence" on their treatment decision chose AS, compared with men with other influential factors, although not statistically significant (44% vs 35%, P = .11). Similar results were also found when men were stratified based on PCa risk groups (favorable risk: 78% vs 67%; unfavorable risk: 17% vs 9%, respectively). Despite a small sample size, a higher proportion of men with non-reassuring confirmatory testing selected AS if influential factors had "a lot of influence" compared to "no influence" on their treatment decisions.
Conclusion: Men's concerns for future bladder, bowel, and sexual function problems, as elicited by a decision aid, may help explain treatment selection that differs from traditional clinical recommendation.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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