Extensive Cerebral Cortical Involvement in Aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder.

Autor: Ramineni KK; Department of Neurology, Yashoda Superspeciality Hospital, Hyderabad, Telangana, India., Jakkani RK; Department of Radiology, Yashoda Superspeciality Hospital, Malakpet, Hyderabad, Telangana, India., Ismail S; Department of Neurology, Yashoda Superspeciality Hospital, Hyderabad, Telangana, India., Malla R; Department of Internal Medicine, Yashoda Superspeciality Hospital, Malakpet, Hyderabad, Telangana, India.
Jazyk: angličtina
Zdroj: Journal of neurosciences in rural practice [J Neurosci Rural Pract] 2021 Apr; Vol. 12 (2), pp. 431-434. Date of Electronic Publication: 2021 Apr 01.
DOI: 10.1055/s-0041-1726621
Abstrakt: Neuromyelitis optica spectrum disorders (NMOSDs) usually manifest with features of long-segment myelitis and/or optic neuritis. Area postrema involvement presents with nausea, vomiting, and intractable hiccups. Cerebral cortical involvement is a relatively uncommon phenomenon. This report describes an interesting case of aquaporin 4 antibody positive NMOSD with extensive cerebral cortical involvement in addition to area postrema and cervicomedullary lesions observed on magnetic resonance imaging. Following immunosuppressive therapy, good clinical response and near-complete resolution of brain imaging abnormalities were observed.
Competing Interests: Conflict of Interest None declared.
(Association for Helping Neurosurgical Sick People. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
Databáze: MEDLINE