Quality of Life in Early Breast Cancer Patients: A Prospective Observational Study Using the FACT-B Questionnaire.

Autor:	Ursini LA; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Nuzzo M; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Rosa C; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy; c.rosa155@gmail.com.; Department of Neuroscience, Imaging and Clinical Sciences, 'G. D'Annunzio' University of Chieti, Chieti, Italy., DI Guglielmo FC; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., DI Tommaso M; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Trignani M; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Borgia M; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Allajbej A; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Patani F; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., DI Carlo C; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Porreca A; Department of Economics, 'G. D'Annunzio' University of Chieti-Pescara, Pescara, Italy., DI Nicola M; Laboratory of Biostatistics, Department of Medical, Oral and Biotechnological Sciences, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Genovesi D; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy.; Department of Neuroscience, Imaging and Clinical Sciences, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Caravatta L; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy.
Jazyk:	angličtina
Zdroj:	In vivo (Athens, Greece) [In Vivo] 2021 May-Jun; Vol. 35 (3), pp. 1821-1828.
DOI:	10.21873/invivo.12443
Abstrakt:	Background/aim: Quality of life (QoL) in early breast cancer (BC) treatment may be affected by acute and late toxicities. This study evaluated the impact of radiotherapy (RT) schedules, treatment-related toxicities, hormone therapy (HT) and age on QoL. Patients and Methods: Ninety-five patients answered the FACT-B 4.0 questionnaire. Acute or late toxicities were recorded at each follow-up visit. Results: The median trend of the QoL subscales was stable during all questionnaires. HT negatively impacted on Functional Assessment of Cancer Therapy-General-Total, functional and emotional wellbeing. No difference was recorded between RT schedules and toxicity. No significant differences for age were detected in QoL. Conclusion: RT seems not to influence QoL of BC patients, in terms of fractionation regimen or RT-related side-effects. Moreover, women having systemic HT experienced a QoL worse than patients treated with RT only. Further and long-term protocols are needed to improve the validity of the tool. (Copyright© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
Databáze:	MEDLINE
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