Efficacy of 1.23% acidulated phosphate fluoride gel on non-cavitated enamel lesions: a randomized clinical trial.

Autor: Goldenfum GM; Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Department of Surgery and Orthopedics, Porto Alegre, RS, Brazil., Silva NC; Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Department of Surgery and Orthopedics, Porto Alegre, RS, Brazil., Almeida IDA; Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Department of Surgery and Orthopedics, Porto Alegre, RS, Brazil., Neves M; Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Department of Preventive and Social Dentistry, Porto Alegre, RS, Brazil., Silva BBE; Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Department of Preventive and Social Dentistry, Porto Alegre, RS, Brazil., Jardim JJ; Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Department of Preventive and Social Dentistry, Porto Alegre, RS, Brazil., Rodrigues JA; Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Department of Surgery and Orthopedics, Porto Alegre, RS, Brazil.
Jazyk: angličtina
Zdroj: Brazilian oral research [Braz Oral Res] 2021 Apr 26; Vol. 35, pp. e038. Date of Electronic Publication: 2021 Apr 26 (Print Publication: 2021).
DOI: 10.1590/1807-3107bor-2021.vol35.0038
Abstrakt: A randomized controlled parallel clinical trial was conducted to evaluate the efficacy of the association of 1.23% topical professional acidulated phosphate fluoride (APF) gel with oral hygiene and dietary instructions on the arrest of active non-cavitated lesions in permanent, mixed, and temporary dentition in children between 3 and 12 years of age. Ninety-eight caries-active children were randomly divided into two groups: a fluoride gel group (n = 49) and a non-fluoridated gel group (n = 49). Each group received up to eight weekly applications of gel, weekly professional toothbrushing with oral hygiene instructions and dietary counselling. Caries lesions were assessed qualitatively through visual-tactile criteria performed in three stages: initial, intermediate, and final. Regression models were applied to identify risk indicators for caries control. Between-group comparison regarding the time taken to arrest the lesions was performed using Chi-squared and Fisher's exact tests. Seventeen children did not receive the allocated intervention, and one was lost to follow-up (n = 80). There was no difference between the control and placebo groups regarding the time to the arrest of the lesion (p >.05). The treatments showed similar results without significant statistical difference (p = 0.33; 95%CI: 0.32-1.48). No adverse effects were observed. It can be concluded that no additional effect of the association of 1.23% APF gel with oral hygiene using fluoride dentifrice and dietary instructions on the arrest of active non-cavitated lesions could be established. We can also confirm the importance of toothbrushing frequency and, consequently, the visible plaque reduction in the control of caries activity. RBR-37V5S3.
Databáze: MEDLINE