An algorithm to personalise the diagnosis of recurrent implantation failure based on theoretical cumulative implantation rate.

Autor:	Rozen G; Reproductive Services, Royal Women's Hospital, Parkville, VIC, Australia.; Department of Obstetrics and Gynaecology, University of Melbourne, Gynaecology Research Centre, Royal Women's Hospital, Parkville, VIC, Australia.; Melbourne IVF, East Melbourne, VIC, Australia., Rogers P; Department of Obstetrics and Gynaecology, University of Melbourne, Gynaecology Research Centre, Royal Women's Hospital, Parkville, VIC, Australia., Teh WT; Reproductive Services, Royal Women's Hospital, Parkville, VIC, Australia.; Department of Obstetrics and Gynaecology, University of Melbourne, Gynaecology Research Centre, Royal Women's Hospital, Parkville, VIC, Australia.; Melbourne IVF, East Melbourne, VIC, Australia., Stern CJ; Reproductive Services, Royal Women's Hospital, Parkville, VIC, Australia.; Department of Obstetrics and Gynaecology, University of Melbourne, Gynaecology Research Centre, Royal Women's Hospital, Parkville, VIC, Australia.; Melbourne IVF, East Melbourne, VIC, Australia., Polyakov A; Reproductive Services, Royal Women's Hospital, Parkville, VIC, Australia.; Department of Obstetrics and Gynaecology, University of Melbourne, Gynaecology Research Centre, Royal Women's Hospital, Parkville, VIC, Australia.; Melbourne IVF, East Melbourne, VIC, Australia.
Jazyk:	angličtina
Zdroj:	Human reproduction (Oxford, England) [Hum Reprod] 2021 May 17; Vol. 36 (6), pp. 1463-1468.
DOI:	10.1093/humrep/deab091
Abstrakt:	Recurrent implantation failure (RIF) is an imprecisely defined disorder lacking a robust scientific basis. The incomplete understanding of RIF provides significant diagnostic and therapeutic challenges, and a better understanding of the underlying issues is necessary to improve outcomes. We propose a novel concept termed 'Theoretical Cumulative Implantation Rate', the calculation of which is based on objective data, to define whether a patient should be diagnosed with RIF. An updated definition to assist with patient counselling and planning research studies, which is more precise and standardised, is well overdue. (© The Author(s) 2021. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
Databáze:	MEDLINE
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