Unique Presentation of Microscopic Polyangiitis: Hearing and Vision Loss, Dysphagia, and Renal Dysfunction.
| Autor: | Badia RR; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA., Hendricks AR; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA., Perez CL; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, USA., Sertich A; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA., Ripley L; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2021 Mar 23; Vol. 13 (3), pp. e14069. Date of Electronic Publication: 2021 Mar 23. |
| DOI: | 10.7759/cureus.14069 |
| Abstrakt: | Microscopic polyangiitis (MPA) is an autoimmune small-vessel vasculitis often positive for perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA), or anti-myeloperoxidase (MPO), that classically affects the lungs, kidneys, and skin. Several atypical presentations of MPA involving other organs have also been reported in the literature. We report a unique case of a patient who presented with rare presentations of MPA: hearing and vision loss, dysphagia, renal dysfunction. Despite the atypical nature of her symptoms, her p-ANCA serology was positive and kidney biopsy was consistent with MPA. Regardless of the bizarre nature of a patient's symptoms, we highlight the importance of considering MPA as a differential diagnosis in the setting of positive p-ANCA serology. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Badia et al.) |
| Databáze: | MEDLINE |
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