The treatment of articular cartilage injuries with mesenchymal stem cells in different animal species.

Autor: Ganiev I; Institute of Fundamental Medicine and Biology of Kazan (Volga region) Federal University, Kazan, Russia., Alexandrova N; Institute of Fundamental Medicine and Biology of Kazan (Volga region) Federal University, Kazan, Russia., Aimaletdinov A; Institute of Fundamental Medicine and Biology of Kazan (Volga region) Federal University, Kazan, Russia., Rutland C; School of Veterinary Medicine and Science, College Road, Sutton Bonington, University of Nottingham, Nottingham, UK., Malanyeva A; Institute of Fundamental Medicine and Biology of Kazan (Volga region) Federal University, Kazan, Russia., Rizvanov A; Institute of Fundamental Medicine and Biology of Kazan (Volga region) Federal University, Kazan, Russia., Zakirova E; Institute of Fundamental Medicine and Biology of Kazan (Volga region) Federal University, Kazan, Russia.
Jazyk: angličtina
Zdroj: Open veterinary journal [Open Vet J] 2021 Jan-Mar; Vol. 11 (1), pp. 128-134. Date of Electronic Publication: 2021 Feb 16.
DOI: 10.4314/ovj.v11i1.19
Abstrakt: One of the major problems observed in veterinary practice is articular cartilage injuries in animals. In terms of agriculture, it leads to their culling from the herd, even if they are highly productive animals. With companion animals, owners usually have to decide between euthanasia or long-term sometimes lifelong treatment of the injury by a veterinarian. The use of mesenchymal stem cells (MSCs) for the treatment of cartilage injury in veterinary medicine is based on the good results observed in preclinical studies, where large animals have been used as experimental models to study the regenerative activity of MSCs. According to the literature, MSCs in veterinary medicine have been used to treat cartilage injury of dogs and horses, whereas sheep and goats are generally models for reproducing the disease in preclinical experimental studies.
Competing Interests: The authors declare that there is no conflict of interest.
Databáze: MEDLINE