| Autor: |
Doorley BM; Department of Pharmacology, Anaquest/BOC Health Care, Murray Hill, New Jersey., Waters SJ, Terrell RC, Robinson JL |
| Jazyk: |
angličtina |
| Zdroj: |
Anesthesiology [Anesthesiology] 1988 Jul; Vol. 69 (1), pp. 89-91. |
| DOI: |
10.1097/00000542-198807000-00013 |
| Abstrakt: |
The minimum alveolar concentration (MAC) of I-653 was determined in six beagle dogs and four New Zealand white rabbits. The MAC values (+/- SD) were 7.2 +/- 1.0 atm % for dogs and 8.9 +/- 0.3 atm % for rabbits. Comparison of these results with published MAC values for other anesthetics indicate that I-653 is one-third to one-eighth as potent as currently available volatile anesthetics (enflurane, isoflurane, and halothane). From these data and previous reports, human MAC was projected to be approximately 5.1 atm %. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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