Stereotactic Radiosurgery for Postoperative Metastatic Surgical Cavities: A Critical Review and International Stereotactic Radiosurgery Society (ISRS) Practice Guidelines.
| Autor: | Redmond KJ; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland. Electronic address: kjanson3@jhmi.edu., De Salles AAF; HCor Neuroscience Institute, Heart Hospital (HCor), São Paulo, São Paulo, Brazil., Fariselli L; Department of Neurosurgery, Unit of Radiotherapy, Fondazione IRCCS Istituto Neurologico C Besta, Milano, Italy., Levivier M; Neurosurgery Service and Gamma Knife Center Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland; Faculty of Biology and Medicine (FBM), University of Lausanne, Lausanne, Switzerland., Ma L; Department of Radiation Oncology, University of California San Francisco, San Francisco, California., Paddick I; Medical Physics Ltd, Queen Square Radiosurgery Centre, London, United Kingdom., Pollock BE; Department of Radiation Oncology and Department of Neurologic Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota., Regis J; Aix-Marseille University, INSERM, UMR 1106, Timone University Hospital, Functional Neurosurgery and Radiosurgery Department, Marseille, France., Sheehan J; Department of Neurosurgery, University of Virginia, Charlottesville, Virginia., Suh J; Department of Radiation Oncology, Taussing Cancer Institute Cleveland Clinic, Cleveland, Ohio., Yomo S; Division of Radiation Oncology, Aizawa Comprehensive Cancer Center, Aizawa Hospital, Matsumoto, Japan., Sahgal A; Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2021 Sep 01; Vol. 111 (1), pp. 68-80. Date of Electronic Publication: 2021 Apr 20. |
| DOI: | 10.1016/j.ijrobp.2021.04.016 |
| Abstrakt: | Purpose: The purpose of this critical review is to summarize the literature specific to single-fraction stereotactic radiosurgery (SRS) and multiple-fraction stereotactic radiation therapy (SRT) for postoperative brain metastases resection cavities and to present practice recommendations on behalf of the ISRS. Methods and Materials: The Medline and Embase databases were used to apply the Preferred Reporting Items for Systematic Reviews and Meta-Analyses approach to search for manuscripts reporting SRS/SRT outcomes for postoperative brain metastases tumor bed resection cavities with a search end date of July 20, 2018. Prospective studies, consensus guidelines, and retrospective series that included exclusively postoperative brain metastases and had at minimum 100 patients were considered eligible. Results: The Embase search revealed 157 manuscripts, of which 77 were selected for full-text screening. PubMed yielded 55 manuscripts, of which 23 were selected for full text screening. We deemed 8 retrospective series, 1 phase 2 prospective study, 3 randomized controlled trials, and 1 consensus contouring paper appropriate for inclusion. The data suggest that SRS/SRT to surgical cavities with prescription doses of 30 to 50 Gy equivalent effective dose (EQD) 2 Conclusions: Although randomized data raise concern for poorer local control after resection cavity SRS than WBRT, these findings may be driven by factors such as conservative prescription doses used in the SRS arm. Retrospective studies suggest high rates of local control after single-fraction SRS and hypofractionated SRT for postoperative brain metastases. With a superior neurocognitive profile and no survival disadvantage to withholding WBRT, the ISRS recommends SRS as first-line treatment for eligible postoperative patients. Emerging data suggest that fractionated SRT may provide superior local control compared with single-fraction SRS, in particular, for large tumor cavity volumes/diameters and potentially for patients with a preoperative diameter greater than 2.5 cm. (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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