In-vivo viscoelastic properties estimation in subcutaneous adipose tissue by integration of poroviscoelastic-mass transport model (pve-MTM) into wearable electrical impedance tomography (w-EIT).
| Autor: | Dharma IA; Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Yayoicho, Inage-ku, Chiba-shi, Chiba 263-8522, Japan.; Department of Mechanical Engineering, Faculty of Industrial Technology, Universitas Islam Indonesia, Jalan Kaliurang KM. 14,5, Sleman, D.I.Yogyakarta 55584, Indonesia., Kawashima D; Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Yayoicho, Inage-ku, Chiba-shi, Chiba 263-8522, Japan., Baidillah MR; Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Yayoicho, Inage-ku, Chiba-shi, Chiba 263-8522, Japan., Darma PN; Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Yayoicho, Inage-ku, Chiba-shi, Chiba 263-8522, Japan., Takei M; Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Yayoicho, Inage-ku, Chiba-shi, Chiba 263-8522, Japan. |
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| Jazyk: | angličtina |
| Zdroj: | Biomedical physics & engineering express [Biomed Phys Eng Express] 2021 Jun 09; Vol. 7 (4). Date of Electronic Publication: 2021 Jun 09. |
| DOI: | 10.1088/2057-1976/abfaea |
| Abstrakt: | In-vivo viscoelastic properties have been estimated in human subcutaneous adipose tissue (SAT) by integration of poroviscoelastic-mass transport model ( pve -MTM) into wearable electrical impedance tomography ( w -EIT) under the influence of external compressive pressure-P.The pve -MTM predicts the ion concentration distributioncmod(t)by coupling the poroviscoelastic and mass transport model to describe the hydrodynamics, rheology, and transport phenomena inside SAT. The w -EIT measures the time-difference conductivity distribution∆γ(t)in SAT resulted from the ion transport. Based on the integration, the two viscoelastic properties which are viscoelastic shear modulus of SATGvand relaxation time of SATτvare estimated by applying an iterative curve-fitting between the normalized average ion concentration distributioncˆmod(t)predicted from pve -MTM and the experimental normalized average ion concentration distributioncˆexp(t)derived from w -EIT. The in-vivo experiments were conducted by applying external compressive pressure-Pon human calf boundary to induce interstitial fluid flow and ion movement in SAT. As a result, the value ofGvwas range from 4.9-6.3 kPa and the value ofτvwas range from 27.50-38.5 s with the value of average goodness-of-fit curve fitting R 2 > 0.76. These values ofGvandτvwere compared to the human and animal tissue from the literature in order to verify this method. The results from pve -MTM provide evidence thatGvandτvplay a role in the predicted value ofcˆmod. (© 2021 IOP Publishing Ltd.) |
| Databáze: | MEDLINE |
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