Work-related violence and depressive disorder among 955,573 employees followed for 6.99 million person-years. The Danish Work Life Course Cohort study: Work-related violence and depression.

Autor: Madsen IEH; National Research Centre for the Working Environment, Copenhagen, Denmark. Electronic address: ihm@nrcwe.dk., Svane-Petersen AC; National Research Centre for the Working Environment, Copenhagen, Denmark., Holm A; The Rockwool Foundation, Copenhagen, Denmark; Western University, London, Canada., Burr H; Unit Psychosocial Factors and Mental Health, Federal Institute for Occupational Safety and Health, Berlin, Germany., Framke E; National Research Centre for the Working Environment, Copenhagen, Denmark., Melchior M; Social Epidemiology Research Group, Institut Pierre Louis d'Épidémiologie et de Santé Publique (IPLESP), INSERM UMR_S 1136, Paris, France., Rod NH; Section of Epidemiology, Department of Public Health, University of Copenhagen, Denmark., Sivertsen B; Department of Health Promotion, Norwegian Institute of Public Health, Bergen, Norway; Department of Research and Innovation, Helse Fonna HF, Haugesund, Norway; Department of Mental Health, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Stansfeld S; Centre for Psychiatry, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Sørensen JK; National Research Centre for the Working Environment, Copenhagen, Denmark., Virtanen M; School of Educational Sciences and Psychology, University of Eastern Finland, Joensuu, Finland; Division of Insurance Medicine, Karolinska Institute, Sweden., Rugulies R; National Research Centre for the Working Environment, Copenhagen, Denmark; Section of Epidemiology, Department of Public Health, University of Copenhagen, Denmark; Department of Psychology, University of Copenhagen, Denmark.
Jazyk: angličtina
Zdroj: Journal of affective disorders [J Affect Disord] 2021 Jun 01; Vol. 288, pp. 136-144. Date of Electronic Publication: 2021 Mar 26.
DOI: 10.1016/j.jad.2021.03.065
Abstrakt: Background: We examined the association between probability of work-related violence and first diagnosis of depressive disorder whilst accounting for the potential selection of individuals vulnerable to depression into occupations with high probability of work-related violence.
Methods: Based on a pre-published study protocol, we analysed nationwide register data from the Danish Work Life Course Cohort study, encompassing 955,573 individuals followed from their entry into the workforce, and free from depressive disorder before work-force entry. Depressive disorder was measured from psychiatric in- and outpatient admissions. We measured work-related violence throughout the worklife by the annual average occupational risk of violence exposure. Using Cox proportional hazards regression, we examined the longitudinal association between work-related violence (both past year and cumulative life-long exposure) and first depressive disorder diagnosis, whilst adjusting for numerous confounders including parental psychiatric and somatic diagnoses, childhood socioeconomic position, and health services use before workforce entry.
Results: The risk of depressive disorder was higher in individuals with high probability of past year work-related violence (hazard ratio: 1.11, 95% CI: 1.06-1.16) compared to employees with low probability of exposure, after adjustment for confounders. Among women, associations were robust across industries, whereas among men, associations were limited to certain industries.
Limitations: Violence was measured on the job group and not the individual level, likely resulting in some misclassification of the exposure.
Conclusions: Work-related violence may increase the risk of depressive disorder, independent of pre-existing risk factors for depressive disorder. These findings underline the importance of preventing work-related violence.
(Copyright © 2021. Published by Elsevier B.V.)
Databáze: MEDLINE
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