Correlation Between Fine Needle Aspiration Cytology (FNAC) and Permanent Histopathology Results in Salivary Gland Masses.

Autor:	AlGhamdi GZ; Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Alzahrani AK; Otolaryngology - Head and Neck Surgery, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Saati H; Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Algarni HM; Orthopaedics, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Alshehri KA; Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Baroom M; Otolaryngology - Head and Neck Surgery, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Awad BI; College of Medicine, Department of Otolaryngology - Head & Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Jeddah, SAU., Algarni M; Otolaryngology - Head and Neck Surgery, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Al-Hakami HA; College of Medicine, Department of Otolaryngology - Head & Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Jeddah, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2021 Mar 18; Vol. 13 (3), pp. e13976. Date of Electronic Publication: 2021 Mar 18.
DOI:	10.7759/cureus.13976
Abstrakt:	Objective Fine-needle aspiration cytology (FNAC) has been widely accepted as a diagnostic safe method for preoperative assessment of salivary gland lesions. This diagnostic tool is inexpensive, easy to perform, relatively painless and it provides useful information to differentiate between benign and malignant salivary gland tumors that helps in the management and surgical planning. This study was undertaken to compare FNAC results with permanent histopathological findings of salivary gland tumors in order to assess its diagnostic accuracy. Materials and methods A total of 37 archived salivary gland FNAC specimens collected between January 2001 and January 2018 were correlated with proven histopathology findings. Sensitivity, specificity, positive and negative predictive values, and diagnostic accuracy were calculated. False negative and false positive cases were determined. Results There were 20 female and 17 male patients. Parotid tumors count for 62.2% and submandibular tumors 37.8%. All cases of malignancy on FNAC were proven to be malignant on the final pathology findings. All cases that were suspicious for malignancy on FNAC were proven to be malignant as well. In addition, three false negative cases were seen and no false positive cases among all FNAC cases. In our series, the overall sensitivity and specificity were 90.3% and 100%, respectively. The positive and negative predictive values were 100% and 57.1%, respectively. The diagnostic accuracy was 91.4%. Conclusion This study demonstrated that FNA cytology of the salivary gland is a useful technique for diagnosis of salivary gland lesions. Insufficient cellularity was the most important factor that resulted in incorrect cytological interpretation. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, AlGhamdi et al.)
Databáze:	MEDLINE
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