Polyphenols: Natural compounds with promising potential in treating polycystic ovary syndrome.

Autor: Mihanfar A; Department of Clinical Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran., Nouri M; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences Tabriz, Iran; Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran., Roshangar L; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Khadem-Ansari MH; Department of Clinical Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran. Electronic address: Ansari_mh@umsu.ac.ir.
Jazyk: angličtina
Zdroj: Reproductive biology [Reprod Biol] 2021 Jun; Vol. 21 (2), pp. 100500. Date of Electronic Publication: 2021 Apr 18.
DOI: 10.1016/j.repbio.2021.100500
Abstrakt: Polyphenols are natural compounds used by plants as a defense system against various stresses. In recent years, the importance of these polyhydroxyphenols has extensively increased due to their potent cardioprotection, anti-carcinogenic, anti-oxidant, anti-apoptotic, and anti-inflammatory properties. Therefore, various studies have reported promising results from the studies investigating their efficacy as a therapeutic strategy in various disorders such as human malignancies, cardiovascular diseases, nervous system impairments, diabetes, metabolic syndrome, aging, and inflammation-associated disorders, as well as a polycystic ovarian syndrome (PCOS). Since oxidative stress, hormonal, metabolic, and endocrine disturbances have been shown to play a crucial role in the initiation/progression of PCOS, polyphenols are suggested to be an effective treatment for this disorder. Therefore, this study aimed to discuss the therapeutic potential of multiple polyphenols in PCOS.
Competing Interests: Declaration of Competing Interest The authors report no declarations of interest.
(Copyright © 2021. Published by Elsevier B.V.)
Databáze: MEDLINE
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