NOTCH1 inhibition prevents GvHD and maintains GvL effect in murine models.

Autor: Baldoni S; Department of Medicine and Sciences of Aging, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Ruggeri L; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Del Papa B; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Sorcini D; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Guardalupi F; Department of Medicine and Sciences of Aging, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Ulbar F; Department of Medicine and Sciences of Aging, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Marra A; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Dorillo E; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Stella A; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Giancola R; Department of Oncology and Hematology, Ospedale Civile 'Santo Spirito', ASL Pescara, Pescara, Italy., Fabi B; Department of Medicine and Sciences of Aging, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Sola R; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Ciardelli S; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., De Falco F; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Rompietti C; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Adamo FM; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Rosati E; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Pierini A; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Sorrentino C; Department of Medicine and Sciences of Aging, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Sportoletti P; Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Di Ianni M; Department of Medicine and Sciences of Aging, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy. mauro.diianni@unich.it.; Department of Oncology and Hematology, Ospedale Civile 'Santo Spirito', ASL Pescara, Pescara, Italy. mauro.diianni@unich.it.
Jazyk: angličtina
Zdroj: Bone marrow transplantation [Bone Marrow Transplant] 2021 Aug; Vol. 56 (8), pp. 2019-2023. Date of Electronic Publication: 2021 Apr 19.
DOI: 10.1038/s41409-021-01297-8
Databáze: MEDLINE