Time lost due to an attack - a novel patient-reported outcome measure for acute migraine treatments.

Autor: Pohl H; Department of Neurology, University Hospital Zurich, Zurich, Switzerland., Benemei S; Careggi University Hospital, Florence, Italy., Garcia-Azorin D; Department of Neurology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Dixon J; MEDIAN Kinzigtal-Klinik, Bad Soden-Salmünster, Germany., Huzzey E; Watford Osteopaths, London, United Kingdom., Ferrari MD; Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands.
Jazyk: angličtina
Zdroj: Cephalalgia : an international journal of headache [Cephalalgia] 2021 Aug; Vol. 41 (9), pp. 1027-1032. Date of Electronic Publication: 2021 Apr 19.
DOI: 10.1177/03331024211006048
Abstrakt: Objective: We propose a new outcome measure to assess the efficacy of migraine treatments translating the approach of the Global Burden of Disease studies from a societal to an individual level: Instead of calculating "years lived with disability", we suggest estimating "time lost due to an attack".
Methods: Time lost due to an attack is calculated by multiplying the duration and the degree of impaired functioning during an attack.
Results: Time lost due to an attack, different from other outcome measures, does not just focus on the short-term analgesic effects of treatments, but rather on the improvement of all migraine symptoms and restoration of functioning, also considering therapy-related impairment. Importantly, time lost due to an attack measures the entire time patients are not functioning normally, from onset to complete resolution.
Conclusions: Time lost due to an attack represents a new paradigm to assess migraine burden in single patients for a patient-centered evaluation of both acute and prophylactic treatments.
Databáze: MEDLINE
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