Outcomes and Risk Factors for Cardiovascular Events in Hospitalized COVID-19 Patients.
Autor: | Xu Q; Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY., Samanapally H; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY., Nathala P; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY., Salunkhe V; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY., Furmanek S; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY., Cahill MN; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY; School of Medicine, University of Louisville, Louisville, KY., McGuffin T; School of Nursing, University of Louisville, Louisville, KY., Mohammad T; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY., Marsili B; Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY., Petrey J; Kornhauser Health Sciences Library, University of Louisville, Louisville, KY., Carrico R; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY., Ramirez J; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY., Akca O; Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY., Clifford SP; Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY., Pahwa S; Department of Cardiovascular & Thoracic Surgery, University of Louisville, Louisville, KY., Roser L; School of Nursing, University of Louisville, Louisville, KY., Kong M; Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY., Huang J; Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY; Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY; Department of Cardiovascular & Thoracic Surgery, University of Louisville, Louisville, KY; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY. Electronic address: jiapeng.huang@louisville.edu. |
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Jazyk: | angličtina |
Zdroj: | Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 2021 Dec; Vol. 35 (12), pp. 3581-3593. Date of Electronic Publication: 2021 Mar 27. |
DOI: | 10.1053/j.jvca.2021.03.035 |
Abstrakt: | Objective: To analyze outcomes and risk factors of cardiovascular events in a metropolitan coronavirus disease 2019 (COVID-19) database, and to perform a subgroup analysis in African American populations to determine whether outcomes and risk factors are influenced by race. Design: Retrospective cohort analysis from March 9, 2020 to June 20, 2020. Setting: Population-based study in Louisville, KY, USA. Participants: Seven hundred adult inpatients hospitalized with COVID-19. Interventions: N/A. Measurements and Main Results: This cohort consisted of 126 patients (18%) with cardiovascular events and 574 patients without cardiovascular events. Patients with cardiovascular events had a much higher mortality rate than those without cardiovascular events (45.2% v 8.7%, p < 0.001). There was no difference between African American and white patients regarding mortality (43.9% v 46.3%, p = 1) and length of stay for survivors (11 days v 9.5 days, p = 0.301). Multiple logistics regression analysis suggested that male, race, lower SaO2/F Conclusions: Cardiovascular events were prevalent and associated with worse outcomes in hospitalized patients with COVID-19. Outcomes of cardiovascular events in African American and white COVID-19 patients were similar after propensity score matching analysis. There were common and unique risk factors for cardiovascular events in African American COVID-19 patients when compared with white patients. Competing Interests: Conflict of Interest None. (Copyright © 2021 Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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