Perspectives of solid organ transplant recipients on medicine-taking: Systematic review of qualitative studies.

Autor: Tang J; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia., Kerklaan J; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia.; Department of Pediatric Nephrology, Academic Medical Center, Emma Children's Hospital, Amsterdam, the Netherlands., Wong G; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia.; Centre for Transplant and Renal Research, Westmead Hospital, Westmead, NSW, Australia., Howell M; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia., Scholes-Robertson N; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia., Guha C; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia., Kelly A; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia., Tong A; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia.
Jazyk: angličtina
Zdroj: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2021 Oct; Vol. 21 (10), pp. 3369-3387. Date of Electronic Publication: 2021 Jun 15.
DOI: 10.1111/ajt.16613
Abstrakt: Medicine-taking among transplant recipients is a complex and ubiquitous task with significant impacts on outcomes. This study aimed to describe the perspectives and experiences of medicine-taking in adult solid organ transplant recipients. Electronic databases were searched to July 2020, and thematic synthesis was used to analyze the data. From 119 studies (n = 2901), we identified six themes: threats to identity and ambitions (impaired self-image, restricting goals and roles, loss of financial independence); navigating through uncertainty and distrust (lacking tangible/perceptible benefits, unprepared for side effects, isolation in decision-making); alleviating treatment burdens (establishing and mastering routines, counteracting side effects, preparing for the unexpected); gaining and seeking confidence (clarity with knowledge, reassurance through collective experiences, focusing on the future outlook); recalibrating to a new normal posttransplant (adjusting to ongoing dependence on medications, in both states of illness and health, unfulfilled expectations); and preserving graft survival (maintaining the ability to participate in life, avoiding rejection, enacting a social responsibility of giving back). Transplant recipients take medications to preserve graft function, but dependence on medications jeopardizes their sense of normality. Interventions supporting the adaptation to medicine-taking and addressing treatment burdens may improve patient satisfaction and capacities to take medications for improved outcomes.
(© 2021 The American Society of Transplantation and the American Society of Transplant Surgeons.)
Databáze: MEDLINE
Externí odkaz: