A case of rapidly progressive upper limb ischemic necrosis in a patient with COVID-19.

Autor:	Makhoul K; Internal Medicine E and Keter B Departments, Rambam Health Care Campus, Haifa, Israel., Shukha Y; Internal Medicine E and Keter B Departments, Rambam Health Care Campus, Haifa, Israel., Hanna LA; Internal Medicine E and Keter B Departments, Rambam Health Care Campus, Haifa, Israel., Nitecki S; Department of Vascular Surgery, Rambam Health Care Campus, Haifa, Israel; Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Leiderman M; Department of Medical Imaging, Rambam Health Care Campus, Haifa, Israel., Hayek T; Internal Medicine E and Keter B Departments, Rambam Health Care Campus, Haifa, Israel; Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Hamoud S; Internal Medicine E and Keter B Departments, Rambam Health Care Campus, Haifa, Israel; Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel. Electronic address: s_hamoud@rmc.gov.il.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 May; Vol. 106, pp. 401-404. Date of Electronic Publication: 2021 Apr 20.
DOI:	10.1016/j.ijid.2021.04.023
Abstrakt:	Background: For more than a year, health systems all over the world have been combating the global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first described in the city of Wuhan in China, presenting as an atypical infection of the lower respiratory tract. Methods: COVID-19 is characterized by multisystemic involvement, and mortality is attributed mainly to the respiratory system involvement, which may lead to severe acute respiratory distress syndrome and respiratory failure. Several COVID-19-associated complications are being increasingly reported, including arterial and venous thromboembolic events that may lead to amputation of the affected limbs. So far, a large number of reports have described hypercoagulability crises leading to amputation of the lower limbs. However, a search of the National Library of Medicine (MEDLINE) revealed no cases of urgent upper limb amputation in COVID-19 patients. Results: This article describes a novel case of upper limb ischemia in a COVID-19 patient, with rapid progression to hand necrosis, requiring urgent through-arm amputation of the upper limb. Conclusions: This case emphasizes the need for anticoagulant therapy in COVID-19 patients and to maintain a constant awareness of the possible thromboembolic COVID-19-related sequelae. (Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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