Physical and functional performance assessment in pediatric oncology: a systematic review.

Autor: Söntgerath R; Department of Pediatric Oncology, Hematology and Hemostaseology, University Hospital Leipzig, Leipzig, Germany., Däggelmann J; Department of Molecular and Cellular Sports Medicine, Institute of Cardiology and Sports Medicine, German Sport University Cologne, Cologne, Germany., Kesting SV; Institute of Preventive Pediatrics, Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.; Kinderklinik München Schwabing, TUM School of Medicine, Department of Pediatrics and Children's Cancer Research Center, Technical University of Munich, Munich, Germany., Rueegg CS; Oslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway., Wittke TC; Krukenberg Cancer Center, University Medicine Halle (Saale), Halle, Germany., Reich S; Working Group Exercise Oncology Division of Medical Oncology, University Clinic Heidelberg and National Centre for Tumor Diseases (NCT), Heidelberg, Germany., Eckert KG; Department of Health Management & Public Health, IST University of Applied Sciences Düsseldorf, Düsseldorf, Germany., Stoessel S; Center for Pediatric and Adolescent Medicine, Childhood Cancer Center, University Medical Center Mainz, Mainz, Germany., Chamorro-Viña C; Faculty of Kinesiology, Calgary, Alberta, Canada., Wiskemann J; Working Group Exercise Oncology Division of Medical Oncology, University Clinic Heidelberg and National Centre for Tumor Diseases (NCT), Heidelberg, Germany., Wright P; Department of Sport, Health Sciences and Social Work, Oxford Brookes University, Oxford, UK., Senn-Malashonak A; Department of Pediatric Oncology, Hematology and Hemostaseology, Goethe University Clinic Frankfurt, Frankfurt am Main, Frankfurt, Germany., Oschwald V; Department of Molecular and Cellular Sports Medicine, Institute of Cardiology and Sports Medicine, German Sport University Cologne, Cologne, Germany., Till AM; Department of Pediatric Hematology and Oncology, University Hospital Schleswig-Holstein, Lübeck, Germany., Götte M; Department of Pediatric Hematology and Oncology, University Hospital Essen, Pediatrics III, Essen, Germany. miriam.goette@uk-essen.de.
Jazyk: angličtina
Zdroj: Pediatric research [Pediatr Res] 2022 Mar; Vol. 91 (4), pp. 743-756. Date of Electronic Publication: 2021 Apr 15.
DOI: 10.1038/s41390-021-01523-5
Abstrakt: Background: Research indicates reduced physical performance from diagnosis into survivorship of pediatric cancer patients. However, there is no systematic information or guideline available on the methods to assess physical performance and function in this population. The purpose was to systematically compile and describe assessments of physical performance and function in patients and survivors of pediatric cancer, including cardiorespiratory fitness, muscle strength, speed, balance, flexibility, functional mobility, gait and motor performance test batteries.
Methods: We searched the databases PubMed, SPORTDiscus, and Cochrane Database and performed abstract and full-text selection of 2619 articles according to the Cochrane Handbook of Systematic Reviews. Information on patients characteristics, assessments, information on validity and reliability, and relevant references was extracted.
Results: In summary, 63 different assessments were found in 149 studies including 11639 participants. Most studies evaluated cardiorespiratory fitness and muscle strength with the majority conducted off treatment. Some outcomes (e.g. speed) and diagnoses (e.g. neuroblastoma) were severely underrepresented. With the exception of gait, leukemia patients represented the largest group of individuals tested.
Conclusions: Insufficient data and patient heterogeneity complicate uniform recommendations for assessments. Our results support researchers and practitioners in selecting appropriate assessment to meet their specific research questions or individual daily practice needs.
Impact: This systematic review includes 149 studies and provides a comprehensive summary of 63 assessments to evaluate cardiorespiratory fitness, muscle strength, speed, balance, flexibility, functional mobility, gait or motor performance test batteries in patients and survivors of pediatric cancer. We present the most studied fields within the pediatric cancer population, which are cardiorespiratory fitness and muscle strength, off treatment phase, and leukemia patients. We propose research priorities by identification of subgroups in terms of cancer type, phase of treatment, and outcome of interest that are underrepresented in studies currently available.
(© 2021. The Author(s).)
Databáze: MEDLINE
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