Environmentally relevant concentrations of benzophenone-3 induce differential histopathological responses in gills and liver of freshwater fish.

Autor: Dos Santos Almeida S; Laboratory of Biotechnology, Central Campus, State University of Goiás, Anápolis, Goiás, 75.132-903, Brazil., Silva Oliveira V; Laboratory of Biotechnology, Central Campus, State University of Goiás, Anápolis, Goiás, 75.132-903, Brazil., Ribeiro Dantas M; Laboratory of Biotechnology, Central Campus, State University of Goiás, Anápolis, Goiás, 75.132-903, Brazil., Luiz Borges L; Laboratory of Biotechnology, Central Campus, State University of Goiás, Anápolis, Goiás, 75.132-903, Brazil.; School of Medical, Pharmaceutical and Biomedical Sciences, Pontifical Catholic University of Goiás, Goiânia, Goiás, Brazil., Teixeira de Sabóia-Morais SM; Laboratory of Cell Behavior, Department of Morphology, Institute of Biological Science, Federal University of Goiás, Goiânia, Goiás, Brazil., Lopes Rocha T; Laboratory of Environmental Biotechnology and Ecotoxicology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Goiás, Brazil., Luiz Cardoso Bailão EF; Laboratory of Biotechnology, Central Campus, State University of Goiás, Anápolis, Goiás, 75.132-903, Brazil. elisaflavia@gmail.com.
Jazyk: angličtina
Zdroj: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Sep; Vol. 28 (33), pp. 44890-44901. Date of Electronic Publication: 2021 Apr 14.
DOI: 10.1007/s11356-021-13839-0
Abstrakt: BP-3 is one of the most used organic UV filters. However, its widespread use and release into aquatic environment can induce ecotoxicological impact on aquatic organisms. Thus, the aim of the current study is to evaluate the gills and liver of freshwater fish Poecilia reticulata subjected to acute exposure (96 h) to BP-3 at environmentally relevant concentrations (10-1000 ng L -1 ). The study was based on adopting qualitative and semi-quantitative approach to assess histopathological changes and integrated the biomarker response in order to investigate organ-specific responses to BP-3 exposure. BP-3 has induced high histopathological index associated with circulatory disturbances, as well as with regressive and immunological changes in gills, whereas the hepatic histopathological index was associated with circulatory disturbances. Moreover, lower BP-3 concentrations were mostly associated with changes in gills, whereas higher BP-3 concentration was mostly linked to hepatic changes. In conclusion, acute exposure to BP-3 at environmentally relevant concentrations had stronger impact on gills than on the liver of P. reticulata, which confirmed organ-specific responses to UV filters.
(© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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