Type-specific incidence, persistence and factors associated with human papillomavirus infection among female sex workers in Benin and Mali, West Africa.

Autor:	Tounkara FK; Département de Médecine Sociale et Préventive, Université Laval, Québec, Canada; Axe Santé des Populations et Pratiques Optimales en Santé, Centre de recherche du CHU de Québec-Université Laval, Québec, Canada., Téguété I; Département de Gynécologie-Obstétrique, CHU Gabriel Toure, BP 267, Bamako, Mali., Guédou FA; Axe Santé des Populations et Pratiques Optimales en Santé, Centre de recherche du CHU de Québec-Université Laval, Québec, Canada; Dispensaire des Infections Sexuellement Transmissibles (DIST), Centre de santé de Cotonou-1, Cotonou, Benin., Talbot D; Département de Médecine Sociale et Préventive, Université Laval, Québec, Canada; Axe Santé des Populations et Pratiques Optimales en Santé, Centre de recherche du CHU de Québec-Université Laval, Québec, Canada., Traoré CB; Département d'Anatomie-Pathologie, CHU Point G, Bamako, Mali., Béhanzin L; École Nationale de Formation des Techniciens Supérieurs en Santé Publique et en Surveillance Épidémiologique, Université de Parakou, Benin., Traoré S; Département de Gynécologie-Obstétrique, CHU Gabriel Toure, BP 267, Bamako, Mali., Goma-Matsétsé E; Dispensaire des Infections Sexuellement Transmissibles (DIST), Centre de santé de Cotonou-1, Cotonou, Benin., Aza-Gnandji M; Dispensaire des Infections Sexuellement Transmissibles (DIST), Centre de santé de Cotonou-1, Cotonou, Benin., Keita B; Association de Recherche de Communication et d'Accompagnement à Domicile de personnes Vivant avec le VIH (ARCAD-SIDA), Bamako, Mali., Guenoun J; Département de Microbiologie et Infectiologie, Centre de recherche du CHU de Montréal, Montréal, Canada., Coutlée F; Département de Microbiologie et Infectiologie, Centre de recherche du CHU de Montréal, Montréal, Canada., Alary M; Département de Médecine Sociale et Préventive, Université Laval, Québec, Canada; Axe Santé des Populations et Pratiques Optimales en Santé, Centre de recherche du CHU de Québec-Université Laval, Québec, Canada; Institut national de santé publique du Québec, Québec, Canada. Electronic address: malary@uresp.ulaval.ca.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 May; Vol. 106, pp. 348-357. Date of Electronic Publication: 2021 Apr 10.
DOI:	10.1016/j.ijid.2021.04.008
Abstrakt:	Objectives: This study in female sex workers (FSWs) aimed to: (1) estimate type-specific incidence and persistence of human papillomavirus (HPV) infection in Cotonou (Benin) and Bamako (Mali); and (2) identify the factors associated with type-specific incidence and persistence of high-risk HPV (HR-HPV) infection. Methods: A 1-year prospective cohort study on cervical cancer screening, and HPV and human immunodeficiency virus (HIV) infections was conducted among FSWs in Cotonou and Bamako from 2017 to 2019. Poisson regression models assessed factors associated with the incidence of HR-HPV infection, while log-binomial regression was performed to identify factors associated with the persistence of HR-HPV infection. Adjusted relative risks (ARR) and 95% confidence intervals (95% CI) were estimated. Results: The incidence of HR-HPV infection was 46.98 per 1000 women-months (predominant types HPV16, HPV35 and HPV59). Factors associated with the incidence of HR-HPV infection were age <20 years (ARR 15.10; 95% CI 3.29-69.19), age at sexual debut <18 years (ARR 6.92; 95% CI 1.97-24.27) and sex work duration ≤1 year (ARR 7.40; 95% CI 1.84-29.69). The persistence of HR-HPV infection at 12 months was 38.7% (most persistent types HPV59, HPV52 and HPV51). Persistence of HR-HPV infection was higher in women with chlamydia (P = 0.031), HIV infection (P < 0.001) and multiple-type HPV infections (P < 0.001). Conclusion: FSWs in West Africa are at high risk of incident and persistent HR-HPV infection, suggesting an urgent need for cervical cancer screening in this population. (Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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