Is the immunogenicity of PD-1 blocking antibodies a confounding variable in murine studies?

Autor: Buss LA; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand. Electronic address: linda.buss@otago.ac.nz., Dachs GU; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Goddard L; Hematology Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Ang AD; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Robinson BA; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand; Canterbury Regional Cancer and Hematology Service, Canterbury District Health Board, Christchurch, New Zealand., Currie MJ; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Hock B; Hematology Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.
Jazyk: angličtina
Zdroj: Immunology letters [Immunol Lett] 2021 Jun; Vol. 234, pp. 13-15. Date of Electronic Publication: 2021 Apr 08.
DOI: 10.1016/j.imlet.2021.04.003
Databáze: MEDLINE