Defining Minor Intracerebral Hemorrhage.

Autor:	Gómez-González A; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain., Lazcano U; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain., Vivanco-Hidalgo RM; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain., Prats-Sánchez L; Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Guisado-Alonso D; Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Delgado-Mederos R; Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Camps-Renom P; Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Martínez Domeño A; Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Cuadrado-Godia E; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain.; DCEXS, Universitat Pompeu Fabra, Barcelona, Spain., Giralt Steinhauer E; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain., Jiménez-Conde J; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain., Soriano-Tárraga C; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain., Avellaneda-Gómez C; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain., Rodríguez-Campello A; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain.; Department of Medicine, Universitat Autónoma de Barcelona, Barcelona, Spain., Martí-Fábregas J; Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Ois A; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain.; Department of Medicine, Universitat Autónoma de Barcelona, Barcelona, Spain., Roquer J; Department of Neurology, Neurology Neurovascular Research Unit Hospital del Mar Research Institute (IMIM), Barcelona, Spain.; Department of Medicine, Universitat Autónoma de Barcelona, Barcelona, Spain.
Jazyk:	angličtina
Zdroj:	Cerebrovascular diseases (Basel, Switzerland) [Cerebrovasc Dis] 2021; Vol. 50 (4), pp. 435-442. Date of Electronic Publication: 2021 Apr 08.
DOI:	10.1159/000515169
Abstrakt:	Background and Purpose: The minor stroke concept has not been analyzed in intracerebral hemorrhage (ICH) patients. Our purpose was to determine the optimal cut point on the NIH Stroke Scale (NIHSS) for defining a minor ICH (mICH) in patients with primary ICH. Methods: An ICH was considered minor if associated with a favorable 3-month outcome (modified Rankin Scale score ≤2). For supratentorial ICH, the discovery cohort consisted of 478 patients prospectively admitted at University Hospital del Mar. Association between NIHSS at admission and 3-month outcome was evaluated with area under the curve-receiver operating characteristics (AUC-ROC) and Youden's index to identify the optimal NIHSS cutoff point to define mICH. External validation was performed in a cohort of 242 supratentorial ICH patients from University Hospital Sant Pau. For infratentorial location, patients from both hospitals (n = 85) were analyzed together. Results: The best -NIHSS cutoff point defining supratentorial-mICH was 6 (AUC-ROC = 0.815 [0.774-0.857] in the discovery cohort and AUC-ROC = 0.819 [0.756-0.882] in the external validation cohort). For infratentorial ICH, the best cutoff point was 4 (AUC-ROC = 0.771 [0.664-0.877]). Using these cutoff points, 40.5% of all primary ICH cases were mICH. Of these, 70.2% were living independently at 3-month follow-up (72% for supratentorial ICH and 56.1% for infratentorial ICH) and 6.5% had died (5.3% for supratentorial ICH, and 14.6% for infratentorial ICH). For patients identified as non-mICH, good 3-month outcome was observed in 11.3% of cases; mortality was 51%. Conclusions: The definition of mICH using the NIHSS cutoff point of 6 for supratentorial ICH and 4 for infratentorial ICH is useful to identify good outcome in ICH patients. (© 2021 S. Karger AG, Basel.)
Databáze:	MEDLINE
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