Preservation of female fertility: The current therapeutic strategy.

Autor: Henry L; Center for Assisted Medical Procreation-University of Liège, CHR Liège Hospital, Liège, Belgium.; Department of Obstetrics and Gynecology, University of Liège, Liège, Belgium., Labied S; Center for Assisted Medical Procreation-University of Liège, CHR Liège Hospital, Liège, Belgium., Jouan C; Center for Assisted Medical Procreation-University of Liège, CHR Liège Hospital, Liège, Belgium., Nisolle M; Center for Assisted Medical Procreation-University of Liège, CHR Liège Hospital, Liège, Belgium.; Department of Obstetrics and Gynecology, University of Liège, Liège, Belgium.
Jazyk: angličtina
Zdroj: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 2022 Jan; Vol. 156 (1), pp. 3-9. Date of Electronic Publication: 2021 Apr 21.
DOI: 10.1002/ijgo.13698
Abstrakt: Background: Preservation of female fertility is a relatively new field in medicine that has grown very rapidly in recent decades. At the beginning, embryo freezing remained the most effective technique. Thereafter, cryopreservation of oocytes and ovarian tissue was considered a secure tool in human fertility preservation. Storage of cortical ovarian tissue is moreover relevant for children, prepubertal girls, and adult patients who cannot benefit from cryopreservation of oocytes.
Objective: To analyze and review recent and relevant scientific literature on medical and social reasons for preservation of fertility.
Methods: The review was conducted based on articles identified from PubMed databases using keywords.
Main Results: Oocyte vitrification allows women to preserve their fertility without the need for fertilization. Nowadays, thousands of healthy children have been born from this procedure. Occurrence of pregnancy depends on two main factors: the number of mature oocytes in storage and the age of the patient at the time of vitrification. Numerous adaptations have been developed to suit the ovarian stimulation regiments to patients with cancer. In young prepubertal girls, freezing of ovarian tissue remains the best and only option.
Conclusion: Oocyte vitrification therefore appears to be the gold standard technique of preserving fertility in young women.
(© 2021 International Federation of Gynecology and Obstetrics.)
Databáze: MEDLINE
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