Prevalence of sleep disturbances in patients with chronic non-cancer pain: A systematic review and meta-analysis.

Autor: Sun Y; Department of Anesthesiology and Pain Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada., Laksono I; Department of Anesthesiology and Pain Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada., Selvanathan J; Department of Anesthesiology and Pain Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada., Saripella A; Department of Anesthesiology and Pain Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada., Nagappa M; Department of Anesthesia and Perioperative Medicine, London Health Sciences Centre and St. Joseph Health Care, Western University, London, Ontario, Canada., Pham C; Department of Anesthesiology and Pain Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada., Englesakis M; Library and Information Services, University Health Network, Toronto, Ontario, Canada., Peng P; Department of Anesthesiology and Pain Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada., Morin CM; School of Psychology, Université Laval, Quebec City, Quebec, Canada; Centre de recherche CERVO/Brain Research Center, Quebec City, Quebec, Canada., Chung F; Department of Anesthesiology and Pain Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address: frances.chung@uhn.ca.
Jazyk: angličtina
Zdroj: Sleep medicine reviews [Sleep Med Rev] 2021 Jun; Vol. 57, pp. 101467. Date of Electronic Publication: 2021 Mar 11.
DOI: 10.1016/j.smrv.2021.101467
Abstrakt: In individuals with chronic pain, sleep disturbances have been suggested to increase suffering, perception of pain, and to negatively affect long-term prognosis. This systematic review and meta-analysis aims to determine the pooled prevalence of sleep disturbances in chronic non-cancer pain patients with no other sleep disorders, using the patient-rated questionnaires Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI). Multiple databases were searched for studies reporting the prevalence of sleep disturbances in chronic pain patients. The meta-analysis was conducted to examine the pooled prevalence of PSQI and ISI data using the inverse-variance random-effects model and to examine mean differences in PSQI scores. The systematic search resulted in 25,486 articles and 20 were included for analysis. In 12 studies using PSQI, the pooled prevalence of sleep disturbance was 75.3% among 3597 chronic pain patients. In eight studies using ISI, the pooled prevalence was 72.9% among 2578 chronic pain patients. The meta-analysis showed a significant mean difference of 2.75 (p < 0.001) in the global PSQI score between the chronic pain group versus the non-chronic pain group. The relatively high prevalence of sleep disturbances in chronic pain patients emphasizes the importance of further characterizing the relationship between sleep and chronic pain.
Competing Interests: Conflicts of interest Frances Chung: Reports research support from the Ontario Ministry of Health and Long-Term Care, University Health Network Foundation, Up-to-date royalties, consultant to Takeda Pharma and Masimo, STOP-Bang proprietary to University Health Network. Charles M. Morin: Reports research grant from Idorsia and Canopy Health; consultants/advisory boards for Eisai, Merck, Sunovion, Pear Therapeutics, Weight Watchers. All other authors have no conflicts to disclose.
(Copyright © 2021. Published by Elsevier Ltd.)
Databáze: MEDLINE
Externí odkaz: