Investigation of neonatal disorders in New World camelids and factors associated with death during and after hospitalization of affected crias.
| Autor: | Frank SL, Nelson BB, Simpson KM, Holt TN, Callan RJ, Hackett ES |
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| Jazyk: | angličtina |
| Zdroj: | Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 2021 Apr 15; Vol. 258 (8), pp. 892-898. |
| DOI: | 10.2460/javma.258.8.892 |
| Abstrakt: | Objective: To assess signalment, clinical findings, and treatments for New World camelids (NWCs) hospitalized for evaluation and treatment of neonatal disorders and investigate associations between these factors and death during and after hospitalization. Animals: 267 NWCs ≤ 30 days of age. Procedures: Medical records of a veterinary teaching hospital were retrospectively reviewed to identify NWCs admitted for evaluation and treatment of neonatal disorders between 2000 and 2010. Signalment, physical examination data, diagnostic findings, treatments, and outcomes were recorded. Factors were examined for association with death during hospitalization and the overall hazard of death by use of multivariable logistic regression and Cox proportional hazards analysis, respectively. Results: The sample comprised alpacas (n = 255) and llamas (12). Median age at admission was 3 days, and median hospitalization time was 2 days; 208 of the 267 (77.9%) neonatal NWCs survived to hospital discharge. Factors associated with increased odds of death during hospitalization included prematurity or dysmaturity, hypothermia, sepsis, toxic changes in neutrophils, and undergoing surgery. The odds of death during hospitalization also increased as anion gap increased. After discharge, 151 of 176 (85.8%) animals had follow-up information available (median follow-up time, 2,932 days); 126 (83%) were alive and 25 (17%) had died. Prematurity or dysmaturity, congenital defects, sepsis, oxygen administration, and undergoing surgery as a neonate were associated with an increased hazard of death; the hazard of death also increased as serum chloride concentration at the time of hospitalization increased. Conclusions and Clinical Relevance: Results suggested the prognosis for survival during and after hospitalization is good for most NWCs hospitalized because of neonatal disorders. |
| Databáze: | MEDLINE |
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