Ocular manifestations of people living with HIV in Tunisia.

Autor:	Saadouli D; Department of Ophthalmology, La Rabta Hospital, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia., Ammari L; Department of Infectious Diseases, La Rabta Hospital, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia., Ben Mansour K; Department of Ophthalmology, La Rabta Hospital, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia., Yahyaoui Y; Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, Tunisia., Aissa S; Department of Infectious Diseases, La Rabta Hospital, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia., Mohamed Ali EA; Department of Ophthalmology, La Rabta Hospital, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia., Yahyaoui S; Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, Tunisia., Tiouri H; Department of Infectious Diseases, La Rabta Hospital, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Jazyk:	angličtina
Zdroj:	Southern African journal of HIV medicine [South Afr J HIV Med] 2021 Mar 19; Vol. 22 (1), pp. 1193. Date of Electronic Publication: 2021 Mar 19 (Print Publication: 2021).
DOI:	10.4102/sajhivmed.v22i1.1193
Abstrakt:	Background: Ocular involvement is a common complication of human immunodeficiency virus (HIV). Knowledge about this topic in Tunisia is limited. Objective: To investigate ophthalmic manifestations in patients living with HIV in Tunisia. Method: This was an observational study, performed between January 2007 and December 2016. We included patients with ocular disorders related to HIV. The data were recorded retrospectively from chart review. Results: Amongst 98 people living with HIV (PLWH), 36 participants (55 eyes) had ocular manifestations. The mean age was 32.2 ± 5.6 years. Twenty-four patients were men and 12 were women. The mean value of CD4+ T-cell count was 156.5 ± 4.2 cells/µL. Bilateral lesions were found in 19 eyes. Best corrected visual acuity was better than 6/12 in 36 eyes. The most common ocular finding was dry eye syndrome (22%), cotton-wool spots (20%) and retinal haemorrhage (16%) followed by cytomegalovirus (CMV) retinitis (9%), anterior uveitis (7%), toxoplasmosis (4%) and tuberculosis retinochoroiditis (7%) Herpetic keratitis (5%), Herpes zoster ophthalmicus (2%) and syphilitic chorioretinitis (2%). Papilledema was found in three eyes (5%). Panuveitis was observed in four eyes (7%): three of them were associated with chorioretinal toxoplasmosis, syphilitic chorioretinitis and CMV retinitis. The fourth was attributable to immune recovery uveitis. A CD4+ T-cell count of ≤ 200 cells/µL was found to be an independent risk factor for developing posterior segment manifestations. Conclusion: Various ophthalmic manifestations were observed in PLWH. The most common lesion was retinopathy. Ocular involvement can be serious leading to poor visual prognosis, which requires close collaboration between the ophthalmologist and infectious disease physician. Competing Interests: The authors declare that they have no financial or personal relationships that may have inappropriately influenced them in writing this article. (© 2021. The Authors.)
Databáze:	MEDLINE
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