Using fresh frozen plasma as an emergency treatment modality for hypertriglyceridaemic acute pancreatitis in a resource-constrained environment: A case report and review of literature.

Autor: Buitendag J; General surgery registrar, Department of Surgery, 71942Tygerberg Hospital, University of Stellenbosch, Western Cape, South Africa JJP Buitendag: General surgery registrar E Theron: Medical officer S Variawa: Medical officer G Oosthuizen: Head of Department of General Surgery., Theron ER; Medical officer, Department of Surgery, Karl Bremer Hospital, University of Stellenbosch, Western Cape, South Africa., Variawa S; Medical officer, Department of Surgery, 37704Ngwelezana Hospital, University of KwaZulu-Natal, Kwa Zulu-Natal, South Africa., Oosthuizen GV; Head of Department, Department of Surgery, 37704Ngwelezana Hospital, University of KwaZulu-Natal, Kwa Zulu-Natal, South Africa.
Jazyk: angličtina
Zdroj: Tropical doctor [Trop Doct] 2021 Oct; Vol. 51 (4), pp. 650-651. Date of Electronic Publication: 2021 Apr 07.
DOI: 10.1177/00494755211005564
Abstrakt: Hypertriglyceridaemia is associated with severe disease such as coronary disease, cerebral vascular accidents and acute pancreatitis. Severe hypertriglyceridaemia is defined as a serum triglyceride value of >55 mmol/L. Hypertriglyceridaemic acute pancreatitis, often found in pregnancy, has a higher mortality rate than the other causes of acute pancreatitis. The cornerstone of treatment is to lower the triglyceride level as quickly as possible. In a resource-constrained environment, plasma exchange is not a viable option. Therefore, exploring the possible efficacity of directly infusing fresh frozen plasma is applicable to rural emergency medicine and may lead to more definitive research. In our case study, we used fresh frozen plasma to enhance the removal of triglyceride because it contains lipoprotein lipase.
Databáze: MEDLINE