A meta-analysis of studies examining associations between resonance Raman spectroscopy-assessed skin carotenoids and plasma carotenoids among adults and children.

Autor:	Jilcott Pitts SB; Department of Public Health, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA., Johnson NS; Department of Public Health, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA., Wu Q; Department of Biostatistics, East Carolina University, East Carolina Heart Institute, Greenville, North Carolina, USA., Firnhaber GC; Nurse Anesthesia Program, East Carolina University College of Nursing, Greenville, North Carolina, USA., Preet Kaur A; Department of Public Health, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA., Obasohan J; National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Bethesda, Maryland, USA.
Jazyk:	angličtina
Zdroj:	Nutrition reviews [Nutr Rev] 2022 Jan 10; Vol. 80 (2), pp. 230-241.
DOI:	10.1093/nutrit/nuab016
Abstrakt:	Context: No meta-analyses appeared to have been conducted to examine overall correlations between resonance Raman spectroscopy (RRS)-assessed skin carotenoids and plasma/serum carotenoids. Objective: To review the available literature and quantify the association between RRS-assessed skin carotenoids and plasma/serum carotenoids via a meta-analysis of observational studies. Data Sources: To identify relevant publications, we searched the PubMed, Embase, CINAHL, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, ProQuest, and Scopus databases in April 2020 for items combining 3 concepts: Raman spectroscopy, skin, and plasma or serum. Data Extraction: Criteria for inclusion were publication in a peer-reviewed journal between 1990 and 2020, available in English language, and results reported as a baseline Pearson correlation coefficient. In teams of 2, the researchers independently reviewed titles and abstracts of 2212 nonduplicate papers with initial screening yielding 62 papers for full-text review, of which 15 were deemed eligible for inclusion. Data Analysis: A random-effects model in R (version 4.0.0) "meta" package was used to analyze the correlation between RRS-assessed skin and plasma/serum carotenoids. A subgroup analysis was conducted for studies involving adults and children, respectively. Conclusions: The 15 studies included 1155 individuals: 963 adults and 192 children. One study included children and adults. The random-effects model yielded an overall correlation of 0.68 (95%CI, 0.61-0.74; I2 = 74%; P < 0.01). The results were similar when grouped by adults and children. Among 963 adults, the correlation in the random-effects model was 0.69 (95%CI, 0.61-0.75; I2 = 78%; P < 0.01). Among 192 children, the correlation in the random-effects model was 0.66 (95%CI, 0.52- 0.77; I2 = 55%; P = 0.06). Overall, there was a positive, statistically significant correlation between RRS-assessed skin carotenoids and plasma/serum carotenoids in a pooled meta-analysis of 15 studies. Systematic Review Registration: PROSPERO (record number 178835). (© The Author(s) 2021. Published by Oxford University Press.)
Databáze:	MEDLINE
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