Impact of prophylactic intracameral moxifloxacin on post-cataract surgery endophthalmitis: data from a tertiary eye care facility in rural India.

Autor: Shenoy P; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India., Goh EJH; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore., Kashikar R; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India., Kohli GM; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India., Sachdeva M; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India., Naman V; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India., Sood D; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India., Bhatia P; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India., Sen P; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India., Agrawal R; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore.; Singapore Eye Research Institute, Singapore, Singapore.; Moorfields Eye Hospital, London, UK., Sen A; Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India. draloksen@gmail.com.
Jazyk: angličtina
Zdroj: International ophthalmology [Int Ophthalmol] 2021 Aug; Vol. 41 (8), pp. 2729-2736. Date of Electronic Publication: 2021 Apr 05.
DOI: 10.1007/s10792-021-01830-0
Abstrakt: Purpose: To study the impact of prophylactic intracameral (IC) moxifloxacin on the incidence, clinical profile and outcomes in eyes developing post-cataract surgery endophthalmitis (PCE).
Methods: This was a single-centre, retrospective, comparative, observational study in which all eyes with PCE between June 2013 and May 2014 without IC moxifloxacin prophylaxis (group A) and June 2015-May 2016 with IC moxifloxacin prophylaxis (group B) were analysed.
Results: A total of 101,815 cataract surgeries were performed in group A and 112,967 in group B. PCE was diagnosed in 179 eyes (0.18%) in group A and 92 eyes (0.08%) in group B (p < 0.001). Greater reduction in risk of PCE was seen in subsidised patients compared to private. The presenting and final visual acuity was significantly better in group B (p < 0.05).
Conclusions: Prophylactic IC moxifloxacin reduced the incidence of PCE with maximum benefit being observed for the subsidised patients and also helped achieve a significantly better visual acuity following the resolution of endophthalmitis.
(© 2021. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
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