No benefit of an adjunctive phototherapy protocol in treatment of periodontitis: A split-mouth randomized controlled trial.

Autor: Preshaw PM; School of Dental Sciences, Newcastle University, Newcastle upon Tyne, UK.; School of Dentistry, University of Dundee, Dundee, UK., Ide M; Faculty of Dentistry Oral and Craniofacial Sciences, King's College London, London, UK., Bissett SM; School of Dental Sciences, Newcastle University, Newcastle upon Tyne, UK., Holliday R; School of Dental Sciences, Newcastle University, Newcastle upon Tyne, UK., Lansdowne N; School of Dental Sciences, Newcastle University, Newcastle upon Tyne, UK., Pickering K; School of Dental Sciences, Newcastle University, Newcastle upon Tyne, UK., Taylor JA; Faculty of Dentistry Oral and Craniofacial Sciences, King's College London, London, UK., Levonian AM; Faculty of Dentistry Oral and Craniofacial Sciences, King's College London, London, UK., Pleasance C; Faculty of Dentistry Oral and Craniofacial Sciences, King's College London, London, UK., Guarnelli ME; Research Centre for the Study of Periodontal and Peri-implant Diseases, University of Ferrara, Ferrara, Italy., Simonelli A; Research Centre for the Study of Periodontal and Peri-implant Diseases, University of Ferrara, Ferrara, Italy., Fabbri C; Research Centre for the Study of Periodontal and Peri-implant Diseases, University of Ferrara, Ferrara, Italy., Farina R; Research Centre for the Study of Periodontal and Peri-implant Diseases, University of Ferrara, Ferrara, Italy., Panagakos FS; West Virginia University School of Dentistry, Morgantown, WV, USA., Trombelli L; Research Centre for the Study of Periodontal and Peri-implant Diseases, University of Ferrara, Ferrara, Italy.
Jazyk: angličtina
Zdroj: Journal of clinical periodontology [J Clin Periodontol] 2021 Aug; Vol. 48 (8), pp. 1093-1102. Date of Electronic Publication: 2021 May 17.
DOI: 10.1111/jcpe.13465
Abstrakt: Aim: To assess the efficacy of a commercially available adjunctive phototherapy protocol ("Perio-1") in treatment of periodontitis.
Materials and Methods: In an examiner-blind, randomized, controlled, split-mouth, multicentre study, 60 periodontitis patients received root surface debridement (RSD) in sextants either alone (control sextants) or with the adjunctive phototherapy protocol (test sextants). Re-evaluation was performed at 6, 12 and 24 weeks.
Results: No statistically significant differences in mean (± standard deviation) clinical attachment level (CAL) change from baseline to week 24 were observed between test (-1.00 ± 1.16 mm) and control sextants (-0.87 ± 0.79 mm) at sites with probing pocket depths (PPDs) ≥5 mm ("deep sites") at baseline (p = .212). Comparisons between test and control sextants for all other parameters (CAL change at all sites, PPD change at deep sites/all sites, bleeding on probing, plaque scores), and for all change intervals, failed to identify any statistically significant differences.
Conclusions: The phototherapy protocol did not provide any additional clinical benefits over those achieved by RSD alone. (German Clinical Trials Register DRKS00011229).
(© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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