Lactate clearance during the first 2 hours after hospital admission: A useful biomarker for predicting 30-day mortality in patients with diabetic ketoacidosis.
| Autor: | Ibrahim A; Department of Emergency Medicine, University of Health Sciences, Haydarpaşa Numune Training And Research Hospital, Istanbul, Turkey., Bayramoglu B; Department of Emergency Medicine, Akcaabat Hackali Baba State Hospital, Trabzon, Turkey., Hokenek NM; Department of Emergency Medicine, University of Health Sciences, Kartal Dr. Lütfi Kırdar City Hospital, Istanbul, Turkey., Tekyol D; Department of Emergency Medicine, University of Health Sciences, Haydarpaşa Numune Training And Research Hospital, Istanbul, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | International journal of clinical practice [Int J Clin Pract] 2021 Jul; Vol. 75 (7), pp. e14204. Date of Electronic Publication: 2021 Apr 12. |
| DOI: | 10.1111/ijcp.14204 |
| Abstrakt: | Objective: This study assessed whether lactate clearance (LC) during the first 2 hours after admission to the emergency department can be used to predict the 30-day mortality of patients diagnosed with diabetic ketoacidosis (DKA). Material and Methods: This was a retrospective observational cohort study of patients admitted to the hospital between January 2014 and January 2019. We identified patients with diabetes who had blood gas test results at the time of admission and 2 hours thereafter. We then calculated the LC in these patients. Patients were divided into groups based on mortality and length of stay (LOS). The groups were compared in terms of age, blood gas pH, osmolarity, glucose level, lactate level on admission and 2 hours thereafter, LC, and bicarbonate (HCO Results: The overall mortality rate was 7.54% (8/107). Age, pH, osmolarity, the HCO Conclusions: LC during the first 2 hours after admission is useful for predicting 30-day mortality in patients with diabetic ketoacidosis. (© 2021 John Wiley & Sons Ltd.) |
| Databáze: | MEDLINE |
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