| Autor: |
Aharaz A; The Capital Region Pharmacy, 2730 Herlev, Denmark.; Multidisciplinary Outpatient Clinic (Fællesambulatoriet, subakutte patientforløb), Copenhagen University Hospital - Amager and Hvidovre, 2300 Copenhagen, Denmark.; Department of Clinical Research, Copenhagen University Hospital - Amager and Hvidovre, 2650 Copenhagen, Denmark., Rasmussen JH; Multidisciplinary Outpatient Clinic (Fællesambulatoriet, subakutte patientforløb), Copenhagen University Hospital - Amager and Hvidovre, 2300 Copenhagen, Denmark.; Department of Emergency Medicine, Copenhagen University Hospital - Bispebjerg and Frederiksberg, 2400 Copenhagen, Denmark., McNulty HBØ; The Capital Region Pharmacy, 2730 Herlev, Denmark., Cyron A; Multidisciplinary Outpatient Clinic (Fællesambulatoriet, subakutte patientforløb), Copenhagen University Hospital - Amager and Hvidovre, 2300 Copenhagen, Denmark., Fabricius PK; Department of Clinical Research, Copenhagen University Hospital - Amager and Hvidovre, 2650 Copenhagen, Denmark., Bengaard AK; The Capital Region Pharmacy, 2730 Herlev, Denmark.; Department of Clinical Research, Copenhagen University Hospital - Amager and Hvidovre, 2650 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark., Sejberg HRC; The Capital Region Pharmacy, 2730 Herlev, Denmark., Simonsen RRL; The Capital Region Pharmacy, 2730 Herlev, Denmark., Treldal C; The Capital Region Pharmacy, 2730 Herlev, Denmark.; Department of Clinical Research, Copenhagen University Hospital - Amager and Hvidovre, 2650 Copenhagen, Denmark., Houlind MB; The Capital Region Pharmacy, 2730 Herlev, Denmark.; Department of Clinical Research, Copenhagen University Hospital - Amager and Hvidovre, 2650 Copenhagen, Denmark.; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark. |
| Abstrakt: |
Medication deprescribing is essential to prevent inappropriate medication use in multimorbid patients. However, experience of deprescribing in Danish Subacute Medical Outpatient Clinics (SMOCs) is limited. The objective of our pilot study was to evaluate the feasibility and sustainability of a collaborative deprescribing intervention by a pharmacist and a physician to multimorbid patients in a SMOC. A randomized controlled pilot study was conducted, with phone follow-up at 30 and 365+ days. A senior pharmacist performed a systematic deprescribing intervention using the Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) criteria, the Danish deprescribing list, and patient interviews. A senior physician received the proposed recommendations and decided which should be implemented. The main outcome was the number of patients having ≥1 medication where deprescribing status was sustained 30 days after inclusion. Out of 76 eligible patients, 72 (95%) were included and 67 (93%) completed the study (57% male; mean age 73 years; mean number of 10 prescribed medications). Nineteen patients (56%) in the intervention group and four (12%) in the control group had ≥1 medication where deprescribing status was sustained 30 days after inclusion ( p = 0.015). In total, 37 medications were deprescribed in the intervention group and five in the control group. At 365+ days after inclusion, 97% and 100% of the deprescribed medications were sustained in the intervention and control groups, respectively. The three most frequently deprescribed medication groups were analgesics, cardiovascular, and gastrointestinal medications. In conclusion, a collaborative deprescribing intervention for multimorbid patients was feasible and resulted in sustainable deprescribing of medication in a SMOC. |
