COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis.

Autor:	Thiam CN; Department of General Medicine, Hospital Kuala Lumpur, Ministry of Health, Jalan Pahang, Kuala Lumpur 50586, Malaysia.; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia., Hasmukharay K; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.; Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia., Lim WC; Department of General Medicine, Hospital Kuala Lumpur, Ministry of Health, Jalan Pahang, Kuala Lumpur 50586, Malaysia.; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia., Ng CC; Department of General Medicine, Hospital Kuala Lumpur, Ministry of Health, Jalan Pahang, Kuala Lumpur 50586, Malaysia.; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia., Pang GHM; Department of General Medicine, Hospital Kuala Lumpur, Ministry of Health, Jalan Pahang, Kuala Lumpur 50586, Malaysia.; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia., Abdullah A; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.; Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, Sungai Buloh 47000, Malaysia., Saedon NI; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.; Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia., Khor HM; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.; Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia., Ong T; Geriatric Medicine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.; Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Jazyk:	angličtina
Zdroj:	Geriatrics (Basel, Switzerland) [Geriatrics (Basel)] 2021 Mar 08; Vol. 6 (1). Date of Electronic Publication: 2021 Mar 08.
DOI:	10.3390/geriatrics6010025
Abstrakt:	(1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (≥60 years) admitted with COVID-19 infection confirmed with RT-PCR from 27 February 2020-25 May 2020 were included in this study. Data on patient characteristics, hospital treatment, and inpatient outcomes were collected via hospital-held electronic medical records. Analysis was done to describe the cohort and identify factors associated with inpatient mortality. (3) Results: 26 participants were included (mean age 76.2 years, female 57.7%). All had at least one comorbid condition and half were frail. About 19.2% had non-respiratory (atypical) symptoms; 23.1% had a severe disease that required intensive care unit monitoring; 46.2% were given COVID-19 targeted therapy. Inpatient mortality and overall complication rates were 23.1% and 42.3%, respectively. Delirium on presentation and lower Ct-value were associated with mortality. (4) Conclusions: Older people with COVID-19 infection have severe infection and poor hospital outcomes. Vigilant hospital care is necessary to address their multimorbidity and frailty, along with appropriate treatment for their infection.
Databáze:	MEDLINE
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