A Rare Case of Osteoinvasive Amelanotic Melanoma of the Nail Unit.
| Autor: | Black AT; Department of Orthopedics, Lenox Hill Hospital Northwell, New York, New York, USA., Lahouti AH; Department of Pathology, Lenox Hill Hospital Northwell, New York, New York, USA., Genco IS; Department of Pathology and Laboratory Medicine, Lenox Hill Hospital Northwell, New York, New York, USA., Yagudayev M; Department of Orthopedics, Lenox Hill Hospital Northwell, New York, New York, USA., Markinson BC; The Leni and Peter W. May Department of Orthopedic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Spielfogel WD; Department of Orthopedics, Lenox Hill Hospital Northwell, New York, New York, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Skin appendage disorders [Skin Appendage Disord] 2021 Feb; Vol. 7 (2), pp. 139-143. Date of Electronic Publication: 2020 Dec 23. |
| DOI: | 10.1159/000512331 |
| Abstrakt: | Introduction: Amelanotic melanoma is a rare subtype, which may be clinically difficult to diagnose due to lack of pigmentation and variable histopathological features. Osteoinvasion is another rare characteristic of melanoma. There are few reports in the literature of amelanotic melanoma of the nail unit (nail bed, matrix, and nail folds) with invasion of bone. Case Presentation: We present a case of a 73-year-old Caucasian male with a 13-month history of an ungual lesion on his right hallux. The lesion was initially treated as a chronic diabetic ulceration with failure to resolve with standard of care. Discussion/conclusion: A heightened index of suspicion for a malignant process is necessary when standard of care fails to lead to improvement or resolution. In these instances, biopsy should be seriously considered. Competing Interests: The authors have no conflicts of interest to declare. (Copyright © 2020 by S. Karger AG, Basel.) |
| Databáze: | MEDLINE |
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