Osteopathy in mild adrenal Cushing's syndrome and Cushing disease.

Autor: Frara S; Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy., Allora A; Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy., di Filippo L; Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy., Formenti AM; Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy., Loli P; Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy., Polizzi E; Dentistry Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Tradati D; Department of Orthopedics and Traumatology, IRCCS Ospedale San Raffaele, Milan, Italy., Ulivieri FM; Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy., Giustina A; Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy. Electronic address: giustina.andrea@hsr.it.
Jazyk: angličtina
Zdroj: Best practice & research. Clinical endocrinology & metabolism [Best Pract Res Clin Endocrinol Metab] 2021 Mar; Vol. 35 (2), pp. 101515. Date of Electronic Publication: 2021 Mar 10.
DOI: 10.1016/j.beem.2021.101515
Abstrakt: Pathophysiology and effects of endogenous glucocorticoid (GC) excess on skeletal endpoints as well as awareness and management of bone fragility are reviewed. Cushing's syndrome (CS) increase the risk of fracture affecting prevalently bone quality. Bone antiresorptive agents (SERMs, bisphosphonates and denosumab) as well as teriparatide increase bone mineral density and in some instances reduce fracture risk. Awareness and management of bone health in CS can be improved.
(Copyright © 2021 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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