Geriatric nutritional risk index predicts all-cause mortality in patients with heart failure: A systematic review and meta-analysis.

Autor:	Dong CH; Department of Health Management Center, Affiliated Hospital of Chengdu University, Jinniu district, Chengdu City, Sichuan Province, China., Chen SY; Department of Vascular Surgery, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, Qingyang district, Chengdu City, Sichuan Province, China., Zeng HL; Department of Health Management Center, Affiliated Hospital of Chengdu University, Jinniu district, Chengdu City, Sichuan Province, China., Yang B; Department of Health Management Center, Affiliated Hospital of Chengdu University, Jinniu district, Chengdu City, Sichuan Province, China., Pan J; Department of Health Management Center, Affiliated Hospital of Chengdu University, Jinniu district, Chengdu City, Sichuan Province, China.
Jazyk:	angličtina
Zdroj:	Clinics (Sao Paulo, Brazil) [Clinics (Sao Paulo)] 2021 Mar 24; Vol. 76, pp. e2258. Date of Electronic Publication: 2021 Mar 24 (Print Publication: 2021).
DOI:	10.6061/clinics/2021/e2258
Abstrakt:	Objectives: Geriatric nutritional risk index (GNRI) might predict the all-cause mortality in patients with heart failure (HF). We performed a meta-analysis to evaluate the correlation between GNRI and all-cause mortality in patients with HF. Methods: We searched the PubMed, Medline, Cochrane Library, and Embase databases for clinical trials investigating the association between GNRI and all-cause mortality in patients with HF, having the primary endpoint as all-cause mortality. Results: In total, nine studies involving 7,659 subjects were included in the systematic review and meta-analysis. The results indicated that major risk and moderate risk GNRI (GNRI<92) was associated with an increased risk of all-cause mortality in elderly patients with HF (hazard ratios [HR] 1.59, 95% confidence intervals [CI] 1.37-1.85). Low risk GNRI (GNRI<98) group predicted all-cause mortality in elderly HF patients (HR 1.56, 95%CI 1.12-2.18) when compared with the high GNRI value group. A subgroup analysis indicated that the relationship between GNRI and HF might differ based on the subtype of heart failure. Conclusions: GNRI is a simple and well-established nutritional assessment tool to predict all-cause mortality in patients with HF.
Databáze:	MEDLINE
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