A life-threatening small bowel obstruction as onset of an unknown sarcoidosis: A case report.

Autor:	Paone G; Department of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic, Geriatric Sciences La Sapienza University of Rome, Rome, Italy.; Department of Public Health and Infectious Diseases, La Sapienza University of Rome, Rome, Italy., Steffanina A; Casilino Hospital, Rome, Italy., De Rose G; Department of Public Health and Infectious Diseases, La Sapienza University of Rome, Rome, Italy., Leonardo G; Casilino Hospital, Rome, Italy., Colombo D; Department of Biomedicine and Prevention, Anatomic Pathology Section, University of Rome Tor Vergata, Rome, Italy., Ricci P; Department of Radiology, Oncology and Pathology, Sapienza University of Rome, Rome, Italy., Sabetta F; Casilino Hospital, Rome, Italy., Vaccaro F; Department of Public Health and Infectious Diseases, La Sapienza University of Rome, Rome, Italy., Rosato E; Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy., Palange P; Department of Public Health and Infectious Diseases, La Sapienza University of Rome, Rome, Italy.
Jazyk:	angličtina
Zdroj:	Respiratory medicine case reports [Respir Med Case Rep] 2021 Mar 09; Vol. 33, pp. 101379. Date of Electronic Publication: 2021 Mar 09 (Print Publication: 2021).
DOI:	10.1016/j.rmcr.2021.101379
Abstrakt:	Sarcoidosis is a systemic granulomatous disorder of unknown etiology characterized by non-caseating granulomas at the site of disease. A confident diagnosis should be established by the evidence of typical granulomas on biopsy and after exclusion of other conditions. Clinically recognizable Gastrointestinal involvement (GI) occurs in less than 1.6% of patients with sarcoidosis, with data revealing small intestine participation in 0.03% of the cases and few anecdotal reports describe a peritoneal presentation. Clinical manifestations of peritoneal sarcoidosis are abdominal discomfort, bloating, weight loss, epigastric and peri-umbilical pain with or without ascites, bowel obstruction. Treatment depends on symptoms and disease activity. Herein we describe the case of a 42-years-old male patient who developed an acute, life-threatening small bowel obstruction as first manifestation of sarcoidosis. To the best of our knowledge, this is the only report showing such extensive and acute onset of intra-abdominal sarcoidosis in the absence of a previous disease manifestation and without pulmonary involvement. Competing Interests: None. (© 2021 The Authors.)
Databáze:	MEDLINE
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