Endorsement of the domains of knee and hip osteoarthritis (OA) flare: A report from the OMERACT 2020 inaugural virtual consensus vote from the flares in OA working group.

Autor: King LK; Department of Medicine, Women's College Research Institute, University of Toronto, 6307 - 76 Grenville Street, 6th Floor, Toronto, Ontario M5S 1B2, Canada. Electronic address: l.king@mail.utoronto.ca., Epstein J; Université de Lorraine, EA 4360 APEMAC, Nancy, France., Cross M; Institute of Bone & Joint Research, University of Sydney, Australia., Buzzi M; Inserm CIC 1433 clinical epidemiology, CHRU, Université de Lorraine, Nancy, France., Buttel T; Department of Rheumatology, Royal North Shore Hospital, The University of Sydney, Inner West Psychology Sydney, Australia., Cembalo SM; Patient research partner, Nancy, France., Spitz E; Université de Lorraine, EA 4360 APEMAC, Metz, France., Adams CL; Department of Rheumatology, Campbelltown Hospital, Sydney, NSW, Australia., Adebajo A; Faculty of Medicine, Dentistry and Health, University of Sheffield, United Kingdom., Bennell K; Centre for Health, Exercise and Sports Medicine, University of Melbourne, Australia., Blanco B; Department of Rheumatology - Hospital Ramon y Cajal, Spain., Courage U; Department of Medicine, University of Jos, Nigeria., Décary S; Department of family medicine and emergency medicine, Université Laval, Canada., Gill M; OMERACT Patient Research Partner, Founder Dragon Claw Charity Ltd, Australia., Gill TK; Adelaide Medical School, The University of Adelaide, Australia., Hajji R; Université de Sousse, Faculté de Médecine de Sousse, Sousse 4000, Tunisia; Hôpital de Sidi Bouzid, Service de Médecine Interne, Sidi Bouzid 9100, Tunisia., Hinman RS; Centre for Health, Exercise & Sports Medicine, Department of Physiotherapy, University of Melbourne, Australia., Jones A; Department of Physical Therapy, University of Alberta, Canada., Li LC; Department of Physical Therapy, University of British Columbia, Arthritis Research Canada, Canada., Mather K; Patient research partner, Toronto, Canada., Mani R; Centre for Health, Activity and Rehabilitation Research, School of Physiotherapy and Pain@Otago Research Theme, University of Otago, Dunedin, New Zealand., Nasef SI; Department of Rheumatology, Faculty of Medicine, Suez Canal University, Egypt., Oo WM; Department of Rehabilitation Medicine, University of Medicine, Mandalay, Myanmar; Department of Rheumatology, Kolling Institute, Royal North Shore Hospital, The University of Sydney, Australia., Østerås N; National Advisory Unit on Rehabilitation in Rheumatology, Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway., Otobo TM; Hospital for Sick Children, University of Toronto, Canada., Ramiro S; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Rheumatology, Zuyderland Medical Center, Heerlen, Netherlands., Sharma S; Department of Physiotherapy, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal; Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand., April KT; School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, Canada; Department of Pediatrics, Faculty of Medicine, University of Ottawa, Canada; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Canada., Touma Z; Department of Medicine, Women's College Research Institute, University of Toronto, 6307 - 76 Grenville Street, 6th Floor, Toronto, Ontario M5S 1B2, Canada., Whittaker JL; Department of Physical Therapy, The University of British Columbia, Arthritis Research Canada, Canada., Wluka AE; Department of Epidemiology and Preventive Medicine, Monash University, Australia., Grosskleg S; Secretariat, OMERACT, University of Ottawa, Ottawa, Ontario, Canada., Hunter DJ; Department of Rheumatology, Royal North Shore Hospital, The University of Sydney, Inner West Psychology Sydney, Australia., Shea B; School of Epidemiology and Public Health, University of Ottawa, Canada., Hawker GA; Department of Medicine, Women's College Research Institute, University of Toronto, 6307 - 76 Grenville Street, 6th Floor, Toronto, Ontario M5S 1B2, Canada., Callahan LF; Division of Rheumatology, Allergy and Immunology, Department of Medicine, Thurston Arthritis Research Center, University of North Carolina, Chapel Hill., March L; Department of Rheumatology, Royal North Shore Hospital, The University of Sydney, Inner West Psychology Sydney, Australia., Guillemin F; Université de Lorraine, EA 4360 APEMAC, Nancy, France.
Jazyk: angličtina
Zdroj: Seminars in arthritis and rheumatism [Semin Arthritis Rheum] 2021 Jun; Vol. 51 (3), pp. 618-622. Date of Electronic Publication: 2021 Mar 20.
DOI: 10.1016/j.semarthrit.2021.03.010
Abstrakt: Objective: Towards developing an instrument to measure knee and hip osteoarthritis (KHOA) flare, the Outcome Measures in Rheumatology (OMERACT) Flares in OA Working Group first sought to identify and define relevant domains of flare in KHOA.
Methods: Guided by OMERACT Filter 2.1, candidate domains were identified from data generated in interviews, in English or French, with persons with KHOA and health professionals (HPs) who treat OA. The first and second rounds of an online Delphi process with patients and HPs, including researchers, selected relevant domains. The third round provided agreement on the selected domains and their definitions. At the virtual OMERACT 2020 workshop, the proposed domains and their definitions were discussed in facilitated breakout groups with patients and HPs. Participants then voted, with consensus set at ≥70%.
Results: Qualitative interviews characterizing OA flare were completed with 29 persons with KHOA and 16 HPs. Content was analyzed and grouped into nine clusters. These candidate domains were included in two Delphi rounds, completed by 91 patients and 165 HPs then 50 patients and 116 HPs, per round, respectively. This resulted in selecting five relevant domains. A final Delphi round, completed by 38 patients and 89 HPs, provided agreement on these domains and their definitions. The OMERACT virtual vote included 27 patients and 106 HPs. The domains and their definitions were endorsed with ≥98% agreement. Domains include: Pain, Swelling, Stiffness, Psychological aspects, and Impact of symptoms, all defined "during flare".
Conclusion: Using OMERACT methodology, we have developed five domains of KHOA flare that were highly endorsed by patients and HPs.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE