Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control.

Autor:	Garibaldi PMM; Serrana State Hospital, Serrana, SP, Brazil., Ferreira NN; Serrana State Hospital, Serrana, SP, Brazil., Moraes GR; Epidemic Service, Serrana, SP, Brazil., Moura JC; Health Department, Serrana, SP, Brazil., Espósito DLA; University of São Paulo, Ribeirao Preto Medical School, Department of Internal Medicine, Ribeirao Preto, SP, Brazil., Volpe GJ; Serrana State Hospital, Serrana, SP, Brazil., Calado RT; University of São Paulo, Ribeirao Preto Medical School, Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirao Preto, SP, Brazil., Fonseca BAL; University of São Paulo, Ribeirao Preto Medical School, Department of Internal Medicine, Ribeirao Preto, SP, Brazil., Borges MC; University of São Paulo, Ribeirao Preto Medical School, Department of Internal Medicine, Ribeirao Preto, SP, Brazil. Electronic address: marcosborges@fmrp.usp.br.
Jazyk:	angličtina
Zdroj:	The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2021 Mar-Apr; Vol. 25 (2), pp. 101570. Date of Electronic Publication: 2021 Mar 23.
DOI:	10.1016/j.bjid.2021.101570
Abstrakt:	SARS-CoV-2 has a high risk of outbreak in long-term skilled nursing facilities (SNF). Coronavirus disease (COVID-19) has high mortality rates among the elderly with chronic health conditions. Following identification of COVID-19 index case in a SNF, serial point-prevalence was implemented with reverse transcription-polymerase chain reaction (RT-PCR) and immunochromatographic assays. Active surveillance and early isolation of infected patients were implemented. Out of 23 SNF residents and 26 healthcare workers (HCW), 18 (78%) and 12 (46%) tested positive for SARS-CoV-2, respectively. High proportion (38%) of positive patients were asymptomatic and RT-PCR was positive up to six days before symptoms. Five (21.74%) residents were hospitalized with COVID-19, and 2 (9%) died; only 1 (4%) HCW needed to be hospitalized and no staff members died. Active surveillance helped COVID-19 control and management in a SNF. Testing symptomatic individuals only may fail to identify and isolate all persons contributing to transmission. In high-risk elderly, only symptoms screening may not be enough for outbreak control. (Copyright © 2021 Sociedade Brasileira de Infectologia. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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