The influence of dietary Motore™ supplement on antioxidant status to Aeromonas hydrophila infection in Rhamdia quelen.

Autor: Franco FW; Laboratory of Plant Extractives, Department of Industrial Pharmacy, Federal University of Santa Maria, RS, Brazil., Bandeira Junior G; Department of Physiology and Pharmacology, Federal University of Santa Maria, RS, Brazil., Dolci GS; Department of Physiology and Pharmacology, Federal University of Santa Maria, RS, Brazil., Barbosa LB; Laboratory of Plant Extractives, Department of Industrial Pharmacy, Federal University of Santa Maria, RS, Brazil., Sartori Oliveira CE; Department of Biochemistry and Molecular Biology, Federal University of Santa Maria, RS, Brazil., de Freitas Souza C; Department of Biochemistry and Molecular Biology, Federal University of Santa Maria, RS, Brazil., Escobar Burger M; Laboratory of Plant Extractives, Department of Industrial Pharmacy, Federal University of Santa Maria, RS, Brazil., Baldisserotto B; Department of Physiology and Pharmacology, Federal University of Santa Maria, RS, Brazil., Heinzmann BM; Laboratory of Plant Extractives, Department of Industrial Pharmacy, Federal University of Santa Maria, RS, Brazil. Electronic address: berta.heinzmann@gmail.com.
Jazyk: angličtina
Zdroj: Microbial pathogenesis [Microb Pathog] 2021 May; Vol. 154, pp. 104871. Date of Electronic Publication: 2021 Mar 24.
DOI: 10.1016/j.micpath.2021.104871
Abstrakt: This study points to evaluate the effects of pre-treatment with standardized dry extract of Curcuma longa (Motore™) added to the diet (0; 250; 500; and 750 mg/kg) on oxidative stress parameters, longevity, and therapeutic success in Rhamdia quelen experimentally infected with Aeromonas hydrophila (MF 372510). After treatment, the liver and kidney were collected to determine non-enzymatic oxidative parameters such as the formation of thiobarbituric acid reactive substances (TBARS), non-protein thiols (NPSH), and quantification of reactive oxygen species (ROS) levels. Also, two enzymatic antioxidant parameters were evaluated: superoxide dismutase (SOD) and catalase (CAT) activities. The results showed an increase of ROS and TBARS levels, a depletion in NPSH, and a decrease of SOD and CAT activities in infected fish compared to control. The highest Motore™ dose minimized the deleterious effect of A. hydrophila infection improving longevity, oxidative status, and survival rate. The addition of 750 mg Motore™/kg feed is recommended for silver catfish in fish farming. Serious economic losses in Rhamdia quelen culture caused by Aeromonas hydrophila infections can be prevented by the addition of Motore™ to the diet.
(Copyright © 2021. Published by Elsevier Ltd.)
Databáze: MEDLINE
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