A study of the microbiological profile of filler-induced skin necrosis.

Autor: Park SJ; Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea., Park JW; Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea., Ahn GR; Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea., Choi SY; Department of Dermatology, Seoul Paik Hospital, Inje University, Seoul, South Korea., Yoo KH; Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea., Li K; Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea., Kim BJ; Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.
Jazyk: angličtina
Zdroj: Clinical and experimental dermatology [Clin Exp Dermatol] 2021 Jul; Vol. 46 (5), pp. 901-905. Date of Electronic Publication: 2021 May 03.
DOI: 10.1111/ced.14653
Abstrakt: Skin necrosis is one of the most severe complications following filler injections, and can result in permanent aesthetic defects. Although an increasing number of studies have addressed the management of dermal filler complications, no study has described the spectrum of microbial pathogens. The aim of this study was to delineate the bacterial profile and prognostic factors of filler-related skin necrosis by reviewing the clinical and microbiological features of these patients. A retrospective medical record review of patients undergoing treatment for skin necrosis induced by fillers was conducted. In total, 10 cases were identified, with injection sites being the nasolabial fold (70%; n = 7), nasal dorsum (20%; n = 2) and nasal tip (10%; n = 1). Reviewing the culture results, the true culture-positive rate was found to be 50% after cases of contamination were excluded. To avoid permanent sequelae, all physicians should be aware of possible secondary infections when treating filler-induced skin necrosis.
(© 2021 British Association of Dermatologists.)
Databáze: MEDLINE