SARS-CoV-2 infection triggering recurrence of Kawasaki disease in a 10-year-old child.

Autor:	Renganathan A; Department of Pediatrics, Holy Family Hospital, New Delhi, India., Garg A; Department of Pediatric Cardiology, Fortis Escorts Heart Institute and Research Centre, New Delhi, India., Chowdhary S; Department of Pediatrics, Holy Family Hospital, New Delhi, India., Raj D; Department of Pediatrics, Holy Family Hospital, New Delhi, India dr_aiims@yahoo.co.in.
Jazyk:	angličtina
Zdroj:	BMJ case reports [BMJ Case Rep] 2021 Mar 24; Vol. 14 (3). Date of Electronic Publication: 2021 Mar 24.
DOI:	10.1136/bcr-2020-240972
Abstrakt:	SARS-CoV-2 infection has recently been related to a spectrum of hyper-inflammatory states in children. There is a striking similarity between these hyper-inflammatory states and Kawasaki disease (KD). We present an interesting case of KD recurrence in a 10-year-old child, who had previously developed KD at 4 years of age. His symptoms included fever, maculopapular rash and altered sensorium. Investigations showed noticeably elevated inflammatory markers, and an echocardiography revealed dilated coronary arteries. SARS-CoV-2 IgG antibodies were positive. The child responded dramatically to intravenous immunoglobulin and intravenous methylprednisolone. It is possible that SARS-CoV-2 infection triggered the recurrence of KD in this child who might have been genetically predisposed to KD. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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