Lobular panniculitis of the thigh as the only cutaneous manifestation of reactivation of Chagas disease in a renal transplant patient: a case report.

Autor:	Oliveira WRP; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Dermatologia, São Paulo, SP, Brasil., Romero-Sandoval K; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Dermatologia, São Paulo, SP, Brasil., Magalhães TS; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Dermatologia, São Paulo, SP, Brasil., Giannotti MA; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Dermatologia, São Paulo, SP, Brasil., Tyring SK; University of Texas Health Science Center, Department of Dermatology. Houston, Texas, United States of America., Costa PVAD; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Dermatologia, São Paulo, SP, Brasil.
Jazyk:	angličtina
Zdroj:	Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2021 Mar 22; Vol. 54, pp. e0269-2020. Date of Electronic Publication: 2021 Mar 22 (Print Publication: 2021).
DOI:	10.1590/0037-8682-0269-2020
Abstrakt:	Reactivation of chronic Trypanosoma cruzi infection in solid organ transplant recipients (SOTRs) has been reported. The patient presented with a 2-week history of two painful erythematous, infiltrated plaques with central ulceration and necrotic crust on the left thigh. She had a history of chronic indeterminate Chagas disease (CD) and had received a kidney transplant before 2 months. Skin biopsies revealed lobular panniculitis with intracellular amastigote forms of T. cruzi. The patient was diagnosed with CD reactivation. Treatment with benznidazole significantly improved her condition. CD reactivation should be suspected in SOTRs living in endemic areas with clinical polymorphism of skin lesions.
Databáze:	MEDLINE
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