Autor: |
Santiago-Rodriguez EI; Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA., Maiorana A; Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA., Peluso MJ; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Hoh R; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Tai V; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Fehrman EA; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Hernandez Y; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Torres L; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Spinelli MA; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Gandhi M; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Kelly JD; Division of HIV, ID and Global Medicine, University of California, San Francisco, San Francisco, CA., Martin JN; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA., Henrich TJ; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA., Deeks SG; Division of Experimental Medicine, University of California, San Francisco, San Francisco, CA., Sauceda JA; Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA. |
Abstrakt: |
We aimed to characterize the variability in the illness experience and recovery process from COVID-19. We conducted in-depth individual interviews with participants enrolled in the Long-term Immunological Impact of Novel Coronavirus (LIINC) cohort study in San Francisco, California from June through October of 2020. Participants were adults who had a previously confirmed positive SARV-CoV-2 nucleic acid amplification test result, had recovered or were recovering from acute infection, and underwent serial evaluations at our clinical research center. We purposefully sampled 24 English- and Spanish-speaking adults with asymptomatic, mild and severe symptomatic infection, including those who were hospitalized, and those with HIV co-infection. Half of our sample (50.0%) identified as Latinx/Hispanic and most of the participants were men (62.5%). We used thematic analysis to characterize the illness experience, recovery process, and mental health impact of experiencing COVID-19 and present clinical data for each participant. Emergent themes were: (1) across symptom profiles and severity, experiencing COVID-19 was associated with psychological distress, (2) among participants with symptomatic infection, the illness experience was characterized by uncertainty in terms of managing symptoms and recovery, and (3) despite wide-ranging illness experiences, participants shared many common characteristics, including health information-seeking behavior facilitated by access to medical care, and uncertainty regarding the course of their illness and recovery. COVID-19 was associated with elevated levels of psychological distress, regardless of symptoms. |