The Utility of Infectious and Neurodiagnostic Testing in Children With Complex Febrile Seizures Requiring Mechanical Ventilation.

Autor:	Yang JH; Department of Neurosciences, 8784University of California, San Diego, CA, USA.; Rady Children's Hospital, San Diego, CA, USA., Villegas R; Department of Pediatrics, 8784University of California, San Diego, CA, USA.; Rady Children's Hospital, San Diego, CA, USA., Khanna S; Department of Pediatrics, 8784University of California, San Diego, CA, USA.; Rady Children's Hospital, San Diego, CA, USA., Kaswick J; Department of Pediatrics, 8784University of California, San Diego, CA, USA.; Rady Children's Hospital, San Diego, CA, USA., Coufal NG; Department of Pediatrics, 8784University of California, San Diego, CA, USA.; Rady Children's Hospital, San Diego, CA, USA., Crawford J; Department of Neurosciences, 8784University of California, San Diego, CA, USA.; Rady Children's Hospital, San Diego, CA, USA., Harvey H; Department of Pediatrics, 8784University of California, San Diego, CA, USA.; Rady Children's Hospital, San Diego, CA, USA.
Jazyk:	angličtina
Zdroj:	Journal of child neurology [J Child Neurol] 2021 Aug; Vol. 36 (9), pp. 735-742. Date of Electronic Publication: 2021 Mar 23.
DOI:	10.1177/08830738211000507
Abstrakt:	A retrospective cohort analysis was performed on 79 consecutive patients between 6 months and 5 years admitted to a tertiary hospital with a diagnosis of complex febrile seizures requiring mechanical ventilation from 2011 to 2017 to determine the utility of infectious and neurologic diagnostics. Intubation was used as a proxy for severity of illness. The overall intensive care unit stay was short (95% intubated <24 hours, 88% admitted <3 days). No life-threatening infections were identified, and none required surgical interventions. Electroencephalogram (EEG) was obtained on 43%, 26% of which were abnormal. Sixty-six percent of patients were discharged on rescue benzodiazepine and 20% with maintenance antiseizure medications. Duration of follow-up averaged 4 years (range 1 month to 9 years); 8 patients (10%) were subsequently diagnosed with epilepsy. Our findings suggest that extensive diagnostic evaluations may not be necessary for children with complex febrile seizures requiring mechanical ventilation although the role of EEG is less understood.
Databáze:	MEDLINE
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